Kanagamuthu Priya, Dhanasekaran Balaji, Karthika S R, Raghavan V K
Present Address: Department of Otorhinolaryngology (ENT), Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam, 603103 TamilNadu India.
Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):502-506. doi: 10.1007/s12070-023-03591-x. Epub 2023 Mar 2.
Otitis externa is an inflammatory condition of the external auditory canal which occurs due to any trauma, changes in the PH of the skin of external auditory canal. The normal PH of the external auditory canal skin should be in the acidic medium. This inhibits the growth of certain infectious microorganisms. Once the external canal skin PH becomes alkaline, the chances of inflammation of the skin increases. To assess the pH of the external auditory canal in cases of otitis externa with secretion and compare the treatment efficacy of treating it with topical anti-inflammatory like ichthammol glycerine, topical steroid cream and oral antibiotics. A prospective observational study involved a total of 120 patients who came with symptoms and signs of external otitis. pH of external canal was measured during first visit and at 42 days. The patients were divided into three groups. First group was treated with Ichthammol glycerine, second group was treated with Ichthammol glycerine with topical steroid cream and third group was treated with oral antibiotics with topical steroid cream. Patients were analyzed based on severity score during first visit, at 7 days, at 21 days and 42 days. This study involved 64(53.3%) patients were male and 56(46.7%) were females. The mean age group involved in the study was 42.50 years. The mean PH value in the external auditory canal during the first visit was alkaline (6.09) and the mean PH value at 42 days was changed to acidic (4.95) which was statistically significant ( = 0.00). There was significant reduction in the severity score in the oral antibiotic with topical steroid cream, followed by IG with topical steroid cream followed by Ichthammol glycerine ( = 0.001). In this study we have analyzed the pH level favorable in causing otitis externa and the best available treatment for the same. It has been observed that the alkaline Ph is more favorable in causing otitis externa. Efficacy of Topical corticosteroid with antibiotics is maximum in the management of otitis externa.
外耳道炎是外耳道的一种炎症性疾病，其发生是由于任何创伤、外耳道皮肤pH值的变化所致。外耳道皮肤的正常pH值应处于酸性介质中。这可抑制某些感染性微生物的生长。一旦外耳道皮肤pH值变为碱性，皮肤发生炎症的几率就会增加。为评估有分泌物的外耳道炎病例中外耳道的pH值，并比较用鱼石脂甘油等局部抗炎药、局部类固醇乳膏和口服抗生素治疗的疗效。一项前瞻性观察性研究共纳入了120例有外耳道炎症状和体征的患者。在首次就诊时和42天时测量外耳道的pH值。患者被分为三组。第一组用鱼石脂甘油治疗，第二组用鱼石脂甘油加局部类固醇乳膏治疗，第三组用口服抗生素加局部类固醇乳膏治疗。根据首次就诊时、7天、21天和42天时的严重程度评分对患者进行分析。本研究中，64例（53.3%）为男性，56例（46.7%）为女性。研究涉及的平均年龄组为42.50岁。首次就诊时外耳道的平均pH值呈碱性（6.09），42天时平均pH值变为酸性（4.95），具有统计学意义（P = 0.00）。口服抗生素加局部类固醇乳膏组的严重程度评分明显降低，其次是鱼石脂甘油加局部类固醇乳膏组，然后是鱼石脂甘油组（P = 0.001）。在本研究中，我们分析了有利于引发外耳道炎的pH水平以及对此的最佳可用治疗方法。据观察，碱性pH值更有利于引发外耳道炎。局部皮质类固醇与抗生素联合使用在外耳道炎的治疗中疗效最佳。
