Faraji Leila, Pourbakht Akram, Haghani Hamid
Department of Audiology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Statistics Department, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):363-371. doi: 10.1007/s12070-022-03452-z. Epub 2023 Jan 18.
Inhibitory function is the basis of many perceptual and non-perceptual abilities in the auditory system. In people with tinnitus, decreased inhibitory function in the central auditory system has been proven. This disorder is caused by an increase in neural activity caused by an imbalance between stimulation and inhibition. The aim of this study was to evaluate and compare inhibitory function in persons who had tinnitus, at and one octave lower than the tinnitus frequency. Studies show that inhibition has very important role in comodulation masking release. According to inhibitory dysfunction in people with tinnitus, in this study we assessed comodulation masking release in tinnitus frequency and one lower octave. Participants were divided into two groups. Group 1 consisted of 7 individuals with unilateral tonal tinnitus at 4 kHz and group 2 included 7 individuals with unilateral tonal tinnitus at 6 kHz. Paired test, in each group separately, showed that the comodulation masking release and Across Frequency comodulation masking release differed significantly between tinnitus frequency and one octave lower in each group ( < 0.05). In fact, the disinhibition in the area around the frequency of the tinnitus seems to be greater than the tinnitus frequency area. It seems that the results of CMRs can be used in planning and managing the treatment of people with tinnitus (such as sound therapy, etc.).
抑制功能是听觉系统中许多感知和非感知能力的基础。在耳鸣患者中,已证实中枢听觉系统的抑制功能下降。这种紊乱是由刺激与抑制失衡导致的神经活动增加所引起的。本研究的目的是评估和比较耳鸣患者在耳鸣频率以及比耳鸣频率低一个倍频程处的抑制功能。研究表明,抑制在共调制掩蔽释放中起着非常重要的作用。根据耳鸣患者的抑制功能障碍,在本研究中我们评估了耳鸣频率以及低一个倍频程处的共调制掩蔽释放。参与者被分为两组。第1组由7名4kHz单侧音调性耳鸣患者组成,第2组包括7名6kHz单侧音调性耳鸣患者。在每组中分别进行配对检验,结果显示每组中耳鸣频率与低一个倍频程处的共调制掩蔽释放和跨频率共调制掩蔽释放存在显著差异(<0.05)。实际上,耳鸣频率周围区域的去抑制似乎大于耳鸣频率区域。似乎共调制掩蔽释放的结果可用于耳鸣患者治疗方案的规划和管理(如声音疗法等)。