School of Food Science and Engineering, South China University of Technology, Guangzhou City, Guangdong Province 510640, China; School of Chinese Ethnic Medicine, Guizhou Minzu University, Guizhou City, Guiyang Province 550025, China.
School of Food Science and Engineering, South China University of Technology, Guangzhou City, Guangdong Province 510640, China.
Food Chem. 2023 Oct 30;424:136367. doi: 10.1016/j.foodchem.2023.136367. Epub 2023 May 12.
Hops extracts and their derivatives have many important biological activities, among them, excellent antibacterial and antioxidant properties make them a promising food preservative. However, poor water solubility limits their application in the food industry. This work aimed to improve the solubility of Hexahydrocolupulone (HHCL) by preparing solid dispersion (SD) and investigating the application of the obtained products (HHCL-SD) in actual food systems. HHCL-SD was prepared by solvent evaporation with PVPK30 as a carrier. The solubility of HHCL was dramatically increased to 24.72 mg/mL（25 ℃)by preparing HHCL-SD, much higher than that of raw HHCL (0.002 mg/mL). The structure of HHCL-SD and the interaction between HHCL and PVPK30 were analyzed. HHCL-SD was confirmed to have excellent antibacterial and antioxidant activities. Furthermore, the addition of HHCL-SD proved to be beneficial for the sensory, nutritional quality, and microbiological safety of fresh apple juice, hence prolonging its shelf-life.
啤酒花提取物及其衍生物具有许多重要的生物活性，其中出色的抗菌和抗氧化性能使它们成为有前途的食品防腐剂。然而，较差的水溶性限制了它们在食品工业中的应用。本工作旨在通过制备固体分散体（SD）来提高六氢大麻酚（HHCL）的溶解度，并研究所得产物（HHCL-SD）在实际食品系统中的应用。HHCL-SD 是通过溶剂蒸发法用 PVPK30 作为载体制备的。通过制备 HHCL-SD，HHCL 的溶解度大大提高至 24.72mg/mL（25℃），远高于原料 HHCL（0.002mg/mL）。分析了 HHCL-SD 的结构以及 HHCL 与 PVPK30 之间的相互作用。HHCL-SD 被证实具有优异的抗菌和抗氧化活性。此外，添加 HHCL-SD 被证明有利于新鲜苹果汁的感官、营养质量和微生物安全性，从而延长了其保质期。
