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氨基酸和肽从胃肠道的吸收。

Amino acid and peptide absorption from the gastrointestinal tract.

作者信息

Webb K E

出版信息

Fed Proc. 1986 Jul;45(8):2268-71.

PMID:3720965
Abstract

Dietary proteins are digested and amino acids from these are utilized by animals to meet body needs for maintenance and production. The form in which these amino acids are absorbed and how they may be transported in the blood seem less certain than once thought. Free amino acids are absorbed and transported in the plasma as well as possibly in the blood cells. These two pools may serve unique functions and therefore deserve individual attention. Peptides are absorbed by the enterocytes. Amino acids in the peptide form appear to be absorbed more readily than free amino acids. The question of whether these peptides are hydrolyzed in the cytosol of the enterocyte or whether they can pass intact into the circulation needs more attention. Evidence suggests that the portal appearance of peptides ranges from negligible contributions to as much as 70% of the amino acids appearing in plasma.

摘要

膳食蛋白质被消化,动物利用其中的氨基酸来满足身体维持和生产的需求。这些氨基酸的吸收形式以及它们在血液中的运输方式似乎比人们曾经认为的更不确定。游离氨基酸在血浆以及可能在血细胞中被吸收和运输。这两个库可能具有独特的功能,因此值得分别关注。肽被肠细胞吸收。肽形式的氨基酸似乎比游离氨基酸更容易被吸收。这些肽是在肠细胞的细胞质中被水解,还是能够完整地进入循环系统,这个问题需要更多的关注。有证据表明,肽在门静脉中的出现量占血浆中氨基酸出现量的比例从可忽略不计到高达70%不等。

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