Second Department of Ophthalmology, Ophthalmiatreion Eye Hospital of Athens, Athens, Greece.
Department of Ophthalmology, National and Kapodistrian University of Athens, 1st University Eye Clinic, G. Gennimatas General Hospital, Athens, Greece.
BMC Ophthalmol. 2023 May 22;23(1):227. doi: 10.1186/s12886-023-02970-w.
We present a case of hypertensive choroidopathy due to malignant hypertension with exudative retinal detachment as a sole finding. We use OCT- angiography for initial diagnosis and report findings from extensive follow up.
A 51-year-old female with no past medical history, presented to our clinic with painless loss of vision in her left eye. Fundus examination revealed only exudative retinal detachment in her left eye that was confirmed with Optical Coherence Tomography. Fluorescein angiography showed hyperfluorescent spots with leakage in late phases. OCTA manifested a focal dark area in the choriocapillaris slab corresponding to flow signal voids, signifying regions of non-perfusion. Her blood pressure was 220/120 mmHG. Complete blood work -up failed to reveal any other possible etiology. During follow-up period of 9 months blood pressure normalized, patient regained visual function and choriocapillaris perfusion was completely restored.
Hypertensive choroidopathy with exudative retinal detachment can be the only sign of malignant hypertension and no pre-existing history of a systemic disease is required in order to become apparent. OCTA reveals areas of non-perfusion at choriocapillaris level, proving that it is an essential tool in the diagnosis and follow up of patients with hypertensive choroidopathy. Finally, we propose that early diagnosis prevents permanent damage of the RPE and leads to complete choroidal remodeling and better visual outcomes.
我们报告了一例由恶性高血压引起的高血压性脉络膜病变,其唯一表现为渗出性视网膜脱离。我们使用 OCT 血管造影进行初步诊断,并报告广泛随访的结果。
一名 51 岁女性,无既往病史,因左眼无痛性视力丧失就诊于我院。眼底检查仅发现左眼渗出性视网膜脱离,经光学相干断层扫描(OCT)证实。荧光素血管造影显示晚期高荧光点伴渗漏。OCTA 显示脉络膜毛细血管层中存在一个局灶性暗区,对应于血流信号缺失,表明无灌注区域。她的血压为 220/120mmHg。全血细胞检查未能发现任何其他可能的病因。在 9 个月的随访期间,血压恢复正常,患者恢复了视力,脉络膜毛细血管灌注完全恢复。
渗出性视网膜脱离的高血压性脉络膜病变可能是恶性高血压的唯一表现,且无需有系统性疾病的既往史即可出现。OCTA 显示脉络膜毛细血管层的无灌注区,证明其是诊断和随访高血压性脉络膜病变患者的重要工具。最后,我们提出早期诊断可防止 RPE 的永久性损伤,并导致完全的脉络膜重塑和更好的视力结果。