Rotsos Tryfon, Andreanos Konstantinos, Blounas Stelios, Brouzas Dimitrios, Ladas Dimitrios S, Ladas Ioannis D
A' Department of Ophthalmology, University of Athens, General Hospital of Athens, Athens, Greece Moorfield's Eye Hospital, London, UK.
Medicine (Baltimore). 2017 Sep;96(39):e8110. doi: 10.1097/MD.0000000000008110.
To investigate malignant hypertension ocular lesions with swept source optical coherence tomography (SS-OCT) and optical coherence tomography angiography (OCT-A).
Visual loss due to malignant hypertension.
Hypertensive chorioretinopathy.
Patients were thoroughly examined on presentation and 30 days after their first visit, with swept-source optical coherence tomography and optical coherence tomography angiography.
Lesions were totally absorbed during the follow-up time. Additionally, they presented fibrin deposits, as multiple solid hyper-reflective structures overlying retinal pigment epithelium, on both-SS-OCT and OCT-A. The last were still detected even larger in size at the last visit of the patients.
These novel imaging examinations allow the ophthalmologist to detect in detail the several clinical manifestations of malignant hypertension on the fundus, and draw useful conclusions about their peculiar pathogenesis.
采用扫频源光学相干断层扫描(SS-OCT)和光学相干断层扫描血管造影(OCT-A)研究恶性高血压性眼部病变。
因恶性高血压导致视力丧失。
高血压性脉络膜视网膜病变。
患者初诊时及首次就诊30天后,采用扫频源光学相干断层扫描和光学相干断层扫描血管造影进行全面检查。
病变在随访期间完全吸收。此外,在SS-OCT和OCT-A上均显示有纤维蛋白沉积物,表现为覆盖在视网膜色素上皮上的多个实性高反射结构。在患者最后一次就诊时,这些沉积物甚至被检测到尺寸更大。
这些新型成像检查使眼科医生能够详细检测眼底恶性高血压的几种临床表现,并对其特殊发病机制得出有用结论。