Li San-Biao, Mei Sheng-Qian, Xu Wen-Bin, Fang Xiang-Qian, Fan Shun-Wu, Huang Li-Bin
Department of Orthopaedics, Jiande Hospital of Integrated Traditional Chinese and Western Medicine, Jiande 311600, Zhejiang, China.
Department of Orthopaedics, Sir Run Run Show Hospital Affiliated to Zhejiang University Medical School, Hangzhou 310016, Zhejiang, China.
Zhongguo Gu Shang. 2023 May 25;36(5):420-7. doi: 10.12200/j.issn.1003-0034.2023.05.005.
To compare the efficacy and muscle injury imaging between oblique lateral lumbar interbody fusion (OLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of single-segment degenerative lumbar spinal stenosis.
The clinical data of 60 patients with single-segment degenerative lumbar spinal stenosis who underwent surgical treatment from January 2018 to October 2019 was retrospectively analyzed. The patients were divided into OLIF groups and TLIF group according to different surgical methods. The 30 patients in the OLIF group were treated with OLIF plus posterior intermuscular screw rod internal fixation. There were 13 males and 17 females, aged from 52 to 74 years old with an average of (62.6±8.3) years old. And 30 patients in the TLIF group were treated with TLIF via the left approach. There were 14 males and 16 females, aged from 50 to 81 years old with an average of (61.7±10.4) years old. General data including operative time, intraoperative blood loss, postoperative drainage volume, and complications were recorded for both groups. Radiologic data including disc height (DH), the left psoas major muscle, multifidus muscle, longissimus muscle area, T2-weighted image hyperintensity changes and interbody fusion or nonfusion were observed. Laboratory parameters including creatine kinase (CK) values on postoperative 1st and 5th days were analyzed. Visual analogue scale(VAS) and Oswestry disability index(ODI) were used to assess clinical efficacy.
There was no significant difference in the operative time between two groups(>0.05). The OLIF group had significantly less intraoperative blood loss and postoperative drainage volume compared to the TLIF group(<0.01). The OLIF group also had DH better recovery compared to the TLIF group (<0.05). There were no significant differences in left psoas major muscle area and the hyperintensity degree before and after the operation in the OLIF group (>0.05). Postoperativly, the area of the left multifidus muscle and longissimus muscle, as well as the mean of the left multifidus muscle and longissimus muscle in the OLIF group, were lower than those in the TLIF group (<0.05) .On the 1st day and the 5th day after operation, CK level in the OLIF group was lower than that in the TLIF group(<0.05). On the 3rd day after operation, the VAS of low back pain and leg pain in the OLIF group were lower than those in the TLIF group (<0.05). There were no significant differences in the ODI of postoperative 12 months, low back and leg pain VAS at 3, 6, 12 months between the two groups(>0.05). In the OLIF group, 1 case of left lower extremity skin temperature increased after the operation, and the sympathetic chain was considered to be injured during the operation, and 2 cases of left thigh anterior numbness occurred, which was considered to be related to psoas major muscle stretch, resulting in a complication rate of 10% (3/30). In the TLIF group, one patient had limited ankle dorsiflexion, which was related to nerve root traction, two patients had cerebrospinal fluid leakage, and the dural sac was torn during the operation, and one patient had incision fat liquefaction, which was related to paraspinal muscle dissection injury, resulting in a complication rate of 13% (4/30). All patients achieved interbody fusion without cage collapse during the 6- month follow-up.
Both OLIF and TLIF are effective in the treatment of single-segment degenerative lumbar spinal stenosis. However, OLIF surgery has obviously advantages, including less intraoperative blood loss, less postoperative pain, and good recovery of intervertebral space height. From the changes in laboratory indexes of CK and the comparison of the left psoas major muscle, multifidus muscle, longissimus muscle area, and high signal intensity of T2 image on imaging, it can be seen that the degree of muscle damage and interference of OLIF surgery is lower than that of TLIF.
比较斜外侧腰椎椎间融合术(OLIF)与经椎间孔腰椎椎间融合术(TLIF)治疗单节段退变性腰椎管狭窄症的疗效及肌肉损伤情况。
回顾性分析2018年1月至2019年10月接受手术治疗的60例单节段退变性腰椎管狭窄症患者的临床资料。根据手术方式不同将患者分为OLIF组和TLIF组。OLIF组30例患者采用OLIF联合后路椎弓根螺钉内固定治疗。其中男13例,女17例,年龄52~74岁,平均(62.6±8.3)岁。TLIF组30例患者采用左侧入路行TLIF治疗。其中男14例,女16例,年龄50~81岁,平均(61.7±10.4)岁。记录两组患者的手术时间、术中出血量、术后引流量及并发症等一般资料。观察两组患者的影像学资料,包括椎间盘高度(DH)、左侧腰大肌、多裂肌、最长肌面积、T2加权像高信号改变及椎间融合或未融合情况。分析两组患者术后第1天和第5天的肌酸激酶(CK)值等实验室指标。采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估临床疗效。
两组患者手术时间比较差异无统计学意义(>0.05)。OLIF组术中出血量及术后引流量均明显少于TLIF组(<0.01)。OLIF组术后DH恢复情况优于TLIF组(<0.05)。OLIF组术前、术后左侧腰大肌面积及高信号程度比较差异无统计学意义(>0.05)。术后,OLIF组左侧多裂肌和最长肌面积以及左侧多裂肌和最长肌平均值均低于TLIF组(<0.05)。术后第1天和第5天,OLIF组CK水平低于TLIF组(<0.05)。术后第3天,OLIF组腰背痛及腿痛VAS评分均低于TLIF组(<0.05)。两组患者术后12个月ODI、术后3个月、6个月、12个月腰腿痛VAS评分比较差异无统计学意义(>0.05)。OLIF组术后1例出现左下肢皮肤温度升高,考虑术中交感神经链损伤,2例出现左大腿前侧麻木,考虑与腰大肌牵拉有关,并发症发生率为10%(3/30)。TLIF组1例患者出现踝关节背伸受限,与神经根牵拉有关;2例患者出现脑脊液漏,术中硬脊膜囊撕裂;1例患者出现切口脂肪液化,与椎旁肌剥离损伤有关,并发症发生率为13%(4/30)。所有患者在6个月随访期间均实现椎间融合,无椎间融合器塌陷。
OLIF和TLIF治疗单节段退变性腰椎管狭窄症均有效。然而OLIF手术具有明显优势,包括术中出血量少、术后疼痛轻、椎间隙高度恢复良好。从CK实验室指标变化以及影像学上左侧腰大肌、多裂肌、最长肌面积及T2像高信号比较来看,OLIF手术对肌肉的损伤及干扰程度低于TLIF。