[腰椎融合内固定术后相邻节段小关节退变对相邻节段疾病的影响]
[Effect of adjacent segmental facet joint degeneration on adjacent segment disease after lumbar fusion and fixation].
作者信息
Mu Yan-Zhi, Chen Xu, Zhao Bin
机构信息
Department of Orthopaedics, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, China.
出版信息
Zhongguo Gu Shang. 2023 May 25;36(5):428-31. doi: 10.12200/j.issn.1003-0034.2023.05.006.
OBJECTIVE
To explore the effect of facet joint degeneration in adjacent segments on the incidence of adjacent segment disease (ASD) after lumbar fusion and fixation.
METHODS
A retrospective analysis was performed on 138 patients who underwent LS posterior lumbar interbody fusion (PLIF) from June 2016 to June 2019. Patients were divided into a degeneration group (68 cases) and a non-degenerative group (70 cases) based on the presence or absence of L facet joint degeneration before surgery (graded using the Weishaupt standard). Age, gender, body mass index (BMI), follow-up time, and preoperative L intervertebral disc degeneration (graded using the Pfirrmann standard) were collected for both groups. Clinical outcomes were evaluated using the visual analogue scale (VAS) and Oswestry disability index (ODI) at 1 and 3 months after surgery. The incidence and time of ASD after surgery were analyzed.
RESULTS
There were no significant differences between the two groups in age, gender, BMI, follow-up time, or preoperative L intervertebral disc degeneration. Both groups showed significant improvement in VAS and ODI at 1 and 3 months after surgery (<0.001), with no significant difference between the groups(>0.05). However, there was a statistically significant difference in the incidence and timing of ASD between the groups (<0.05). The degeneration group had 2 cases of ASD in gradeⅠdegeneration, 4 cases of ASD in gradeⅡdegeneration, and 7 cases of ASD in grade Ⅲ degeneration. There was a statistically significant difference between the number of patients with grade Ⅲ degeneration and those with gradesⅠandⅡASD (<0.0167, Bonferroni correction).
CONCLUSION
Preoperative degeneration of adjacent articular processes will increase the risk of ASD after lumbar fusion fixation, whereas gradeⅢ degeneration will further increase the risk.
目的
探讨腰椎融合内固定术后相邻节段小关节退变对相邻节段疾病(ASD)发生率的影响。
方法
对2016年6月至2019年6月行腰4、5椎体间后路腰椎椎间融合术(PLIF)的138例患者进行回顾性分析。根据术前腰4、5小关节是否退变(采用魏绍普标准分级)将患者分为退变组(68例)和非退变组(70例)。收集两组患者的年龄、性别、体重指数(BMI)、随访时间以及术前腰4、5椎间盘退变情况(采用菲尔曼标准分级)。术后1个月和3个月采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估临床疗效。分析术后ASD的发生率及发生时间。
结果
两组患者在年龄、性别、BMI、随访时间或术前腰4、5椎间盘退变方面差异均无统计学意义。两组患者术后1个月和3个月时VAS和ODI均显著改善(<0.001),组间差异无统计学意义(>0.05)。然而,两组患者ASD的发生率及发生时间差异有统计学意义(<0.05)。退变组中,Ⅰ度退变有2例发生ASD,Ⅱ度退变有4例发生ASD,Ⅲ度退变有7例发生ASD。Ⅲ度退变患者与Ⅰ度和Ⅱ度ASD患者数量之间差异有统计学意义(<0.0167,Bonferroni校正)。
结论
术前相邻关节突退变会增加腰椎融合内固定术后ASD的发生风险,而Ⅲ度退变会进一步增加该风险。