Mu Yan-Zhi, Chen Xu, Zhao Bin
Department of Orthopaedics, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang 453100, Henan, China.
Zhongguo Gu Shang. 2023 May 25;36(5):428-31. doi: 10.12200/j.issn.1003-0034.2023.05.006.
To explore the effect of facet joint degeneration in adjacent segments on the incidence of adjacent segment disease (ASD) after lumbar fusion and fixation.
A retrospective analysis was performed on 138 patients who underwent LS posterior lumbar interbody fusion (PLIF) from June 2016 to June 2019. Patients were divided into a degeneration group (68 cases) and a non-degenerative group (70 cases) based on the presence or absence of L facet joint degeneration before surgery (graded using the Weishaupt standard). Age, gender, body mass index (BMI), follow-up time, and preoperative L intervertebral disc degeneration (graded using the Pfirrmann standard) were collected for both groups. Clinical outcomes were evaluated using the visual analogue scale (VAS) and Oswestry disability index (ODI) at 1 and 3 months after surgery. The incidence and time of ASD after surgery were analyzed.
There were no significant differences between the two groups in age, gender, BMI, follow-up time, or preoperative L intervertebral disc degeneration. Both groups showed significant improvement in VAS and ODI at 1 and 3 months after surgery (<0.001), with no significant difference between the groups(>0.05). However, there was a statistically significant difference in the incidence and timing of ASD between the groups (<0.05). The degeneration group had 2 cases of ASD in gradeⅠdegeneration, 4 cases of ASD in gradeⅡdegeneration, and 7 cases of ASD in grade Ⅲ degeneration. There was a statistically significant difference between the number of patients with grade Ⅲ degeneration and those with gradesⅠandⅡASD (<0.0167, Bonferroni correction).
Preoperative degeneration of adjacent articular processes will increase the risk of ASD after lumbar fusion fixation, whereas gradeⅢ degeneration will further increase the risk.
探讨腰椎融合内固定术后相邻节段小关节退变对相邻节段疾病(ASD)发生率的影响。
对2016年6月至2019年6月行腰4、5椎体间后路腰椎椎间融合术(PLIF)的138例患者进行回顾性分析。根据术前腰4、5小关节是否退变(采用魏绍普标准分级)将患者分为退变组(68例)和非退变组(70例)。收集两组患者的年龄、性别、体重指数(BMI)、随访时间以及术前腰4、5椎间盘退变情况(采用菲尔曼标准分级)。术后1个月和3个月采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估临床疗效。分析术后ASD的发生率及发生时间。
两组患者在年龄、性别、BMI、随访时间或术前腰4、5椎间盘退变方面差异均无统计学意义。两组患者术后1个月和3个月时VAS和ODI均显著改善(<0.001),组间差异无统计学意义(>0.05)。然而,两组患者ASD的发生率及发生时间差异有统计学意义(<0.05)。退变组中,Ⅰ度退变有2例发生ASD,Ⅱ度退变有4例发生ASD,Ⅲ度退变有7例发生ASD。Ⅲ度退变患者与Ⅰ度和Ⅱ度ASD患者数量之间差异有统计学意义(<0.0167,Bonferroni校正)。
术前相邻关节突退变会增加腰椎融合内固定术后ASD的发生风险,而Ⅲ度退变会进一步增加该风险。