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687 例报告因牙科材料不良反应的患者中的一般疾病和药物。

General diseases and medications in 687 patients reporting on adverse effects from dental materials.

机构信息

Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.

Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

出版信息

Clin Oral Investig. 2023 Aug;27(8):4447-4457. doi: 10.1007/s00784-023-05064-5. Epub 2023 May 22.

Abstract

OBJECTIVES

Examination of patients claiming adverse effects from dental materials can be very challenging. Particularly, systemic aspects must be considered besides dental and orofacial diseases and allergies. Therefore, the aim of this study was to investigate a cohort of 687 patients reporting on adverse effects from dental materials focusing on findings related to known general diseases or conditions or medication-related findings with relevance to their subjective complaints.

METHODS

Six hundred eighty-seven patients visiting a specialized consultation on claimed adverse effects from dental materials were retrospectively investigated for their subjective complaints, findings related to known general diseases or conditions, medication-related findings, dental and orofacial findings, or allergies with relevance to their subjective complaints.

RESULTS

The most frequent subjective complaints were burning mouth (44.1%), taste disorders (28.5%), and dry mouth (23.7%). In 58.4% of the patients, dental and orofacial findings relevant to their complaints could be found. Findings related to known general diseases or conditions or medication-related findings were found in 28.7% or 21.0% of the patients, respectively. Regarding medications, findings related to antihypertensives (10.0%) and psychotropic drugs (5.7%) were found most frequently. Relevant diagnosed allergies toward dental materials were found in 11.9%, hyposalivation in 9.6% of the patients. In 15.1% of the patients, no objectifiable causes for the expressed complaints could be found.

CONCLUSIONS

For patients complaining of adverse effects from dental materials, findings related to known general diseases or conditions and medications should be given particular consideration, while still in some patients, no objectifiable causes for their complaints can be found.

CLINICAL RELEVANCE

For patients complaining about adverse effects from dental materials, specialized consultations and close collaboration with experts from other medical fields are eligible.

摘要

目的

检查声称对牙科材料有不良反应的患者可能极具挑战性。特别是,除了口腔和颌面疾病以及过敏外,还必须考虑全身方面。因此,本研究的目的是调查 687 名报告对牙科材料不良反应的患者,重点关注与已知一般疾病或状况相关的发现或与他们的主观投诉相关的药物相关发现。

方法

回顾性调查 687 名专门就诊于声称对牙科材料有不良反应的患者,了解他们的主观投诉、与已知一般疾病或状况相关的发现、与药物相关的发现、口腔和颌面发现或与他们的主观投诉相关的过敏情况。

结果

最常见的主观投诉是口腔烧灼感(44.1%)、味觉障碍(28.5%)和口干(23.7%)。在 58.4%的患者中,可以发现与他们的投诉相关的口腔和颌面发现。在 28.7%或 21.0%的患者中发现了与已知一般疾病或状况或药物相关的发现。关于药物,发现最常与降压药(10.0%)和精神药物(5.7%)相关。在 11.9%的患者中发现了对牙科材料的相关过敏诊断,在 9.6%的患者中发现了唾液分泌减少。在 15.1%的患者中,无法找到患者表达的投诉的客观原因。

结论

对于抱怨对牙科材料有不良反应的患者,应特别注意与已知一般疾病或状况和药物相关的发现,而在某些患者中,仍无法找到他们投诉的客观原因。

临床意义

对于抱怨牙科材料不良反应的患者,应提供专门的咨询,并与其他医学领域的专家密切合作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edd4/10415419/548a46659f64/784_2023_5064_Fig1_HTML.jpg

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