Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, US.
*Rody G. Bou Chaaya and Zhihao Zhu contributed equally.
Methodist Debakey Cardiovasc J. 2023 May 16;19(3):78-90. doi: 10.14797/mdcvj.1219. eCollection 2023.
Structural interventions play a crucial role in the management of adult congenital heart disease (ACHD). In recent years, this field has seen significant advancements in catheter-based procedures despite limited investment from industry and lack of device development specific to this population. Because each patient is unique in their anatomy, pathophysiology, and surgical repair, many devices are used off-label with a "best fit" strategy. Therefore, continuous innovation is needed to adapt what is available to ACHD and to increase collaboration with industry and regulatory bodies to develop dedicated equipment. These innovations will further advance the field and offer this growing population less invasive options with fewer complications and faster recovery times. In this article, we summarize some of the contemporary structural interventions performed in adults with congenital defects and present cases performed at Houston Methodist to better illustrate them. We aim to offer a greater understanding of the field and stimulate interest in this rapidly growing specialty.
结构性介入在成人先天性心脏病(ACHD)的治疗中起着至关重要的作用。近年来,尽管该领域的产业投资有限,且针对该人群的器械研发不足,但经导管介入技术仍取得了显著进展。由于每位患者的解剖结构、病理生理学和手术修复都具有独特性,因此许多器械都是超适应证使用,采用“最佳适配”策略。因此,需要不断创新,以适应 ACHD 的需要,并加强与产业界和监管机构的合作,开发专用设备。这些创新将进一步推动该领域的发展,为这个不断增长的人群提供创伤更小、并发症更少、恢复更快的治疗选择。本文总结了一些在成人先天性心脏病患者中实施的现代结构性介入治疗方法,并展示了在休斯顿卫理公会医院实施的病例,以更好地说明这些方法。我们旨在提供对该领域的更深入理解,并激发对这个快速发展的专业领域的兴趣。