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以慢性阑尾炎形式表现的阑尾子宫内膜异位症:一例报告

Appendiceal Endometriosis Presenting As Chronic Appendicitis: A Case Report.

作者信息

Klein Sarah, Tourangeau-Young RaeAnn, Biglione Alejandro

机构信息

Internal Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Clearwater, USA.

Internal Medicine, Wellington Regional Medical Center, Wellington, USA.

出版信息

Cureus. 2023 Apr 19;15(4):e37825. doi: 10.7759/cureus.37825. eCollection 2023 Apr.

DOI:10.7759/cureus.37825
PMID:37214070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10198667/
Abstract

The origin of endometriosis has multiple theories, with controversy over which may demonstrate the prominent pathophysiology. The most common extra-pelvic organ system affected by endometriosis is the gastrointestinal tract. Gastrointestinal endometriosis (GE) accounts for 3 to 37% of all endometriosis cases, and appendiceal endometriosis is present in around 3% of GE cases, therefore constituting less than 1% of all endometriosis cases. In this report, we present a 24-year-old female with a past medical history significant for endometriosis status post two excisional laparoscopies who presented with eight months' duration of right lower quadrant pain, constant and stabbing, with rebound tenderness. Appendectomy and histopathology demonstrated focal endometriosis, diffuse serosal fibrovascular adhesions involving the appendiceal serosa/subserosa, as well as a dilated lumen filled with hemorrhagic content. When the appendix is not considered in endometriosis pathology, patients are at increased risk for unresolved pain and further laparoscopic procedures. Prophylactic appendectomy appears to be a worthwhile consideration in patients with chronic pelvic pain, given the high frequency of appendiceal pathology.

摘要

子宫内膜异位症的起源有多种理论,关于哪种理论能体现其主要病理生理学存在争议。受子宫内膜异位症影响最常见的盆腔外器官系统是胃肠道。胃肠道子宫内膜异位症(GE)占所有子宫内膜异位症病例的3%至37%,阑尾子宫内膜异位症约占GE病例的3%,因此占所有子宫内膜异位症病例的比例不到1%。在本报告中,我们介绍了一名24岁女性,既往有子宫内膜异位症病史,接受过两次腹腔镜切除术,此次因右下象限疼痛持续8个月前来就诊,疼痛持续且呈刺痛,有反跳痛。阑尾切除术及组织病理学检查显示局灶性子宫内膜异位症、累及阑尾浆膜/浆膜下的弥漫性浆膜纤维血管粘连,以及充满血性内容物的扩张管腔。若在子宫内膜异位症病理检查中未考虑阑尾情况,患者出现疼痛未缓解及进一步行腹腔镜手术的风险会增加。鉴于阑尾病变的高发生率,对于慢性盆腔疼痛患者,预防性阑尾切除术似乎是一个值得考虑的选择。

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本文引用的文献

1
Endometriosis Pain Management: a Review.子宫内膜异位症疼痛管理:综述。
Curr Pain Headache Rep. 2020 Jul 15;24(9):49. doi: 10.1007/s11916-020-00884-6.
2
Appendicular endometriosis: A case report and review of literature.阑尾子宫内膜异位症:一例病例报告及文献综述
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Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment.子宫内膜异位症:分类、发病机制、诊断及治疗的进展与争议
F1000Res. 2019 Apr 23;8. doi: 10.12688/f1000research.14817.1. eCollection 2019.
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Am J Obstet Gynecol. 2019 Apr;220(4):354.e1-354.e12. doi: 10.1016/j.ajog.2018.12.039. Epub 2019 Jan 6.
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Gastrointestinal and Urinary Tract Endometriosis: A Review on the Commonest Locations of Extrapelvic Endometriosis.胃肠道及泌尿道子宫内膜异位症:盆腔外子宫内膜异位症最常见部位的综述
Adv Med. 2018 Sep 26;2018:3461209. doi: 10.1155/2018/3461209. eCollection 2018.
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Current and emerging treatment options for endometriosis.内异症的现有和新兴治疗选择。
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The role of appendectomy in gynaecologic surgery: a canadian retrospective case series.阑尾切除术在妇科手术中的作用:一项加拿大回顾性病例系列研究
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Endometriosis of the appendix: A diagnostic dilemma.阑尾子宫内膜异位症:诊断难题。
Indian J Surg. 2010 Jul;72(Suppl 1):315-7. doi: 10.1007/s12262-010-0087-3. Epub 2010 Oct 20.
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Acute appendicitis caused by endometriosis: a case report.子宫内膜异位症引起的急性阑尾炎:一例报告
J Med Case Rep. 2011 Apr 11;5:144. doi: 10.1186/1752-1947-5-144.
10
Endometriosis and the appendix: a case series and comprehensive review of the literature.子宫内膜异位症与阑尾:病例系列及文献综述
Fertil Steril. 2006 Aug;86(2):298-303. doi: 10.1016/j.fertnstert.2005.12.076. Epub 2006 Jul 7.