Huang Jiaguo, Ding Hongxiang, Feng Chao, Mao Dikai, Tai Shengcheng
Department of Urology, Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, People's Republic of China.
School of Medicine, Hangzhou Normal University, Hangzhou, People's Republic of China.
Infect Drug Resist. 2023 May 16;16:3035-3040. doi: 10.2147/IDR.S410962. eCollection 2023.
Hematuria occurring in patients with acute kidney injury caused by Corona Virus Disease 2019 (COVID-19) infection has been reported. However, cases of macroscopic hematuria in COVID-19 patients leading to a severe decrease in hemoglobin have not been reported heretofore. Herein, we describe the case of a 56-year-old male patient who suffered from spontaneous prostatic hemorrhage caused by thrombocytopenia and coagulation dysfunction associated with COVID-19 infection, which manifested as macroscopic hematuria, bladder blood clot tamponade and severe hemoglobin decline. Prostatic hemorrhage was diagnosed by endoscopy. There was no recurrence of macroscopic hematuria after undergoing transurethral prostate electrocoagulation for hemostasis, infusing plasma to supplement coagulation factors and taking finasteride. One month after the bleeding event, the patient's blood routine reexamination revealed that the platelet count returned to the normal value and coagulation was normal.
有报道称新型冠状病毒肺炎(COVID - 19)感染所致急性肾损伤患者会出现血尿。然而,此前尚未有COVID - 19患者出现肉眼血尿并导致血红蛋白严重下降的病例报道。在此,我们描述一例56岁男性患者,其因COVID - 19感染相关的血小板减少和凝血功能障碍,发生自发性前列腺出血,表现为肉眼血尿、膀胱血凝块填塞及血红蛋白严重下降。通过内镜检查诊断为前列腺出血。经尿道前列腺电凝止血、输注血浆补充凝血因子及服用非那雄胺后,肉眼血尿未再复发。出血事件发生一个月后,患者血常规复查显示血小板计数恢复至正常水平,凝血功能正常。