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难以与硬皮病相鉴别的嗜酸性筋膜炎:一例报告

Eosinophilic fasciitis difficult to differentiate from scleroderma: A case report.

作者信息

Lan Tian-Yi, Wang Zi-Han, Kong Wei-Ping, Wang Jin-Ping, Zhang Nan, Jin Di-Er, Luo Jing, Tao Qing-Wen, Yan Ze-Ran

机构信息

Graduate College, Beijing University of Chinese Medicine, Beijing 100029, China.

Traditional Chinese Medicine Department of Rheumatism, China-Japan Friendship Hospital, Beijing 100029, China.

出版信息

World J Clin Cases. 2023 May 6;11(13):3092-3098. doi: 10.12998/wjcc.v11.i13.3092.

Abstract

BACKGROUND

Eosinophilic fasciitis (EF) is a rare connective tissue disease that can cause swelling and sclerosis of the extremities, and special attention is needed to differentiate EF from systemic sclerosis. Misdiagnosis or omission markedly delays treatment of EF, and severe skin sclerosis in advanced stages can cause joint contracture and tendon retraction, worsening the patient's prognosis and quality of life.

CASE SUMMARY

We report a case of EF in a young woman diagnosed by tissue biopsy, confirming the difficulty of differential diagnosis with scleroderma.

CONCLUSION

Focusing on skin manifestations, completing tissue biopsy and radiography can help diagnose EF effectively. Clinicians should enhance their understanding of the differences between EF and scleroderma, and early diagnosis and standardized treatment can improve the prognosis of patients with EF.

摘要

背景

嗜酸性筋膜炎(EF)是一种罕见的结缔组织疾病,可导致四肢肿胀和硬化,需要特别注意将EF与系统性硬化症相鉴别。误诊或漏诊会显著延误EF的治疗,晚期严重的皮肤硬化可导致关节挛缩和肌腱挛缩,使患者的预后和生活质量恶化。

病例摘要

我们报告1例经组织活检确诊的年轻女性EF病例,证实了与硬皮病鉴别诊断的困难。

结论

关注皮肤表现、完善组织活检及影像学检查有助于有效诊断EF。临床医生应加强对EF与硬皮病差异的认识,早期诊断和规范治疗可改善EF患者的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ead6/10198086/f67caa8a483c/WJCC-11-3092-g001.jpg

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