Gooding Gregory D, Protudjer Jennifer L, Gabrielli Sofianne, Mulé Pasquale, Shand Greg, Zhang Xun, McCusker Christine, Noya Francisco J, Harvey Maria, Chalifour Mélodie, Sicard Catherine, Abrams Elissa, Amiel Jacques-Alexandre, Ngo Thanh-Thao, Bonnici Andre, MacDonald Noni, Ben-Shoshan Moshe
Division of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.
Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Front Allergy. 2023 May 5;4:1101247. doi: 10.3389/falgy.2023.1101247. eCollection 2023.
We aimed to determine vaccine hesitancy and the main barriers associated with the 2019 novel coronavirus, SARS-CoV-2 (COVID-19) vaccination among families of children diagnosed with food/drug/environmental allergies.
Between May and June 2021, we approached 146 families seen at the outpatient allergy clinic at the Montreal Children's Hospital and a community allergy practice were invited to complete an anonymous online survey on COVID-19 and vaccination attitudes and behaviour. Uni and multivariable logistic regressions were compared to estimate factors associated with vaccine hesitancy.
Among all patients, 24.1% reported vaccine hesitancy. The large majority of parents (95.2%) believed that vaccines work. The most common barrier to vaccination was fear of adverse side effects (57.0%). One-third of participants (31.5%) reported that a history of food, venom and drug allergy was a contraindication for COVID-19 vaccination. Fifty-nine (60.8%) participants stated that the dissemination of additional information would increase their willingness to be vaccinated. Most (96.9%) parents reported that their children's vaccinations were up to date. Hesitant families were more likely to be parents of children aged 6-10 years, be of Asian descent, report that mRNA vaccines are riskier than traditional vaccines, and report that the vaccine should not be given if the child has a history of allergic reaction to vaccines.
Vaccine hesitancy exists mainly among certain ethnic groups and families with young children. Allergies to food, venom and drug allergy are commonly perceived as contraindications for COVID-19 vaccination. Knowledge translation activities addressing parental concerns will help increase vaccination rates.
我们旨在确定2019新型冠状病毒SARS-CoV-2（COVID-19）疫苗接种犹豫情况以及在被诊断患有食物/药物/环境过敏的儿童家庭中与接种相关的主要障碍。
在2021年5月至6月期间，我们联系了在蒙特利尔儿童医院门诊过敏诊所就诊的146个家庭，并邀请一家社区过敏诊所完成一项关于COVID-19及疫苗接种态度和行为的匿名在线调查。采用单变量和多变量逻辑回归来评估与疫苗犹豫相关的因素。
在所有患者中，24.1%报告有疫苗犹豫情况。绝大多数家长（95.2%）认为疫苗是有效的。接种疫苗最常见的障碍是担心有不良副作用（57.0%）。三分之一的参与者（31.5%）报告称食物、毒液和药物过敏史是COVID-19疫苗接种的禁忌证。59名（60.8%）参与者表示，更多信息的传播会增加他们接种疫苗的意愿。大多数（96.9%）家长报告称他们孩子的疫苗接种是最新的。犹豫的家庭更有可能是6至10岁孩子的家长、亚裔血统，报告称mRNA疫苗比传统疫苗风险更高，并且报告称如果孩子有疫苗过敏反应史则不应接种疫苗。
疫苗犹豫主要存在于某些种族群体和有幼儿的家庭中。食物、毒液和药物过敏通常被视为COVID-19疫苗接种的禁忌证。针对家长担忧开展知识转化活动将有助于提高疫苗接种率。
