Laboratory of Organic Chemistry, Wageningen University, Stippeneng 4, Wageningen 6708 WE, The Netherlands.
School of Pharmaceutical Sciences and Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, People's Republic of China.
Langmuir. 2023 Jun 6;39(22):7613-7622. doi: 10.1021/acs.langmuir.3c00280. Epub 2023 May 22.
The ability to tailor polymer brush coatings to the last nanometer has arguably placed them among the most powerful surface modification techniques currently available. Generally, the synthesis procedures for polymer brushes are designed for a specific surface type and monomer functionality and cannot be easily employed otherwise. Herein, we describe a modular and straightforward two-step grafting-to approach that allows introduction of polymer brushes of a desired functionality onto a large range of chemically different substrates. To illustrate the modularity of the procedure, gold, silicon oxide (SiO), and polyester-coated glass substrates were modified with five different block copolymers. In short, the substrates were first modified with a universally applicable poly(dopamine) primer layer. Subsequently, a grafting-to reaction was performed on the poly(dopamine) films using five distinct block copolymers, all of which contained a short poly(glycidyl methacrylate) segment and longer segment of varying chemical functionality. Ellipsometry, X-ray photoelectron spectroscopy, and static water contact angle measurements confirmed successful grafting of all five block copolymers to the poly(dopamine)-modified gold, SiO, and polyester-coated glass substrates. In addition, our method was used to provide direct access to binary brush coatings, by simultaneous grafting of two different polymer materials. The ability to synthesize binary brush coatings further adds to the versatility of our approach and paves the way toward production of novel multifunctional and responsive polymer coatings.
将聚合物刷涂层精确调整到最后一个纳米的能力可以说是将其置于目前可用的最强大的表面改性技术之一。通常，聚合物刷的合成程序是针对特定的表面类型和单体功能设计的，否则不能轻易使用。在此，我们描述了一种模块化和直接的两步接枝方法，该方法允许将具有所需功能的聚合物刷引入到广泛的化学性质不同的基底上。为了说明该程序的模块化，我们使用五种不同的嵌段共聚物对金、氧化硅（SiO）和聚酯涂层玻璃基底进行了修饰。简而言之，首先用普遍适用的聚多巴胺（poly(dopamine)）引发剂层对基底进行修饰。随后，在聚多巴胺（poly(dopamine)）薄膜上进行接枝反应，使用了五种不同的嵌段共聚物，它们都包含短的聚（甲基丙烯酸缩水甘油酯）段和具有不同化学功能的较长段。椭圆测量法、X 射线光电子能谱和静态水接触角测量法证实了所有五种嵌段共聚物都成功地接枝到了聚多巴胺（poly(dopamine)）修饰的金、SiO 和聚酯涂层玻璃基底上。此外，我们的方法还用于通过同时接枝两种不同的聚合物材料来提供合成二元刷涂层的直接途径。合成二元刷涂层的能力进一步增加了我们方法的多功能性，并为生产新型多功能和响应性聚合物涂层铺平了道路。
