Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
McGill University-Montreal Neurological Institute, Neuropsychology and Cognitive Neuroscience, Montreal, Canada; International Laboratory for Brain, Music and Sound Research (BRAMS), Montreal, Canada.
Brain Res. 2023 Aug 15;1813:148418. doi: 10.1016/j.brainres.2023.148418. Epub 2023 May 20.
The insula contributes to the detection of salient events during goal-directed behavior and participates in the coordination of motor, multisensory, and cognitive systems. Recent task-fMRI studies with trained singers suggest that singing experience can enhance the access to these resources. However, the long-term effects of vocal training on insula-based networks are still unknown. In this study, we employed resting-state fMRI to assess experience-dependent differences in insula co-activation patterns between conservatory-trained singers and non-singers. Results indicate enhanced bilateral anterior insula connectivity in singers relative to non-singers with constituents of the speech sensorimotor network. Specifically, with the cerebellum (lobule V-VI) and the superior parietal lobes. The reversed comparison showed no effects. The amount of accumulated singing training predicted enhanced bilateral insula co-activation with primary sensorimotor areas representing the diaphragm and the larynx/phonation area-crucial regions for cortico-motor control of complex vocalizations-as well as the bilateral thalamus and the left putamen. Together, these findings highlight the neuroplastic effect of expert singing training on insula-based networks, as evidenced by the association between enhanced insula co-activation profiles in singers and the brain's speech motor system components.
脑岛参与了目标导向行为中显著事件的检测，并参与了运动、多感觉和认知系统的协调。最近对受过训练的歌手进行的任务 fMRI 研究表明，歌唱经验可以增强对这些资源的获取。然而，声乐训练对基于脑岛的网络的长期影响仍不清楚。在这项研究中，我们使用静息态 fMRI 来评估音乐学院训练的歌手和非歌手之间脑岛共同激活模式的经验依赖性差异。结果表明，与非歌手相比，歌手的双侧前脑岛连接增强，其组成部分包括言语感觉运动网络。具体而言，与小脑（叶 V-VI）和上顶叶。相反的比较没有效果。累积的歌唱训练量预测了双侧脑岛与代表隔膜和喉/发声区域的初级感觉运动区域的共同激活增强，这些区域对于复杂发声的皮质运动控制至关重要，以及双侧丘脑和左侧壳核。总的来说，这些发现强调了专家歌唱训练对基于脑岛的网络的神经可塑性影响，这可以通过歌手的脑岛共同激活谱增强与大脑言语运动系统成分之间的关联来证明。
