Department of Orthopedic Surgery, Linkou Branch, Musculoskeletal Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan City, Taiwan.
Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Taoyuan Branch, Taoyuan City, Taiwan.
Sci Rep. 2023 May 22;13(1):8208. doi: 10.1038/s41598-023-35488-8.
We examined the incidence and causative factors of surgical site infection (SSI) following osteosynthesis for pelvic ring injury by reviewing the data of 97 consecutive patients with pelvic ring injuries treated between 2014 and 2019. Osteosyntheses, including internal or external skeletal fixation with plates or screws, were performed based on fracture type and patient's condition. Fractures were treated surgically, with a 36 months minimum follow-up period. Eight (8.2%) patients experienced SSI. The most common causative pathogen was Staphylococcus aureus. Patients with SSI had significantly worse functional outcomes at 3, 6, 12, 24, and 36 months than those without. For patients with SSI, the average Merle d'Aubigné and Majeed scores at 3, 6, 12, 24, and 36 months after injury were 2.4, 4.1, 8.0, 11.0, and 11.3, and 25.5, 32.1, 47.9, 61.9, and 63.3, respectively. Patients with SSI had a higher likelihood of undergoing staged operations (50.0 vs. 13.5%, p = 0.02), more surgeries for associated injuries (6.3% vs. 2.5%, p = 0.04), higher likelihood of Morel-Lavallee lesions (50.0% vs. 5.6%, p = 0.002), higher incidence of diversional colostomy (37.5% vs. 9.0%, p = 0.05), and longer intensive care unit stay (11.1 vs. 3.9 days, p = 0.001) than those without. The contributing factors for SSI were Morel-Lavallee lesions (odds ratio [OR] 4.55, 95% confidence interval [95% CI] 3.34-50.0) and other surgeries for associated injuries (OR 2.37, 95% CI 1.07-5.28). Patients with SSI after osteosynthesis for pelvic ring injuries may have worse short-term functional outcomes.
我们回顾了 2014 年至 2019 年间连续 97 例骨盆环损伤患者的资料,以评估骨盆环损伤内固定术后手术部位感染(SSI)的发生率和致病因素。根据骨折类型和患者情况,采用钢板或螺钉等内、外骨骼固定进行内固定。骨折采用手术治疗,随访时间至少 36 个月。8 例(8.2%)患者发生 SSI。最常见的致病病原体是金黄色葡萄球菌。与无 SSI 的患者相比,发生 SSI 的患者在术后 3、6、12、24 和 36 个月时的功能结局明显更差。对于 SSI 患者,受伤后 3、6、12、24 和 36 个月时,Merle d'Aubigné 和 Majeed 平均评分分别为 2.4、4.1、8.0、11.0 和 11.3,25.5、32.1、47.9、61.9 和 63.3。发生 SSI 的患者更有可能进行分期手术(50.0%比 13.5%,p=0.02),更有可能进行相关损伤的多次手术(6.3%比 2.5%,p=0.04),更有可能发生Morel-Lavallee 损伤(50.0%比 5.6%,p=0.002), Diversional 结肠造口术的发生率更高(37.5%比 9.0%,p=0.05),入住重症监护病房的时间更长(11.1 天比 3.9 天,p=0.001)。SSI 的致病因素是 Morel-Lavallee 损伤(优势比[OR]4.55,95%置信区间[95%CI]3.34-50.0)和其他相关损伤的手术(OR 2.37,95%CI 1.07-5.28)。骨盆环损伤内固定术后发生 SSI 的患者可能会出现短期功能结局更差。