Xu Jin, Du Hongyu, Shi Huanran, Song Jianing, Yu Jingquan, Zhou Yanhong
Department of Horticulture, Zijingang Campus, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, P.R. China.
Hainan Institute, Zhejiang University, Sanya, 572025, P.R. China.
J Exp Bot. 2023 Oct 13;74(19):6119-6130. doi: 10.1093/jxb/erad187.
Post-translational modifications affect protein functions and play key roles in controlling biological processes. Plants have unique types of O-glycosylation that are different from those of animals and prokaryotes, and they play roles in modulating the functions of secretory proteins and nucleocytoplasmic proteins by regulating transcription and mediating localization and degradation. O-glycosylation is complex because of the dozens of different O-glycan types, the widespread existence of hydroxyproline (Hyp), serine (Ser), and threonine (Thr) residues in proteins attached by O-glycans, and the variable modes of linkages connecting the sugars. O-glycosylation specifically affects development and environmental acclimatization by affecting diverse physiological processes. This review describes recent studies on the detection and functioning of protein O-glycosylation in plants, and provides a framework for the O-glycosylation network that underlies plant development and resistance.
翻译后修饰影响蛋白质功能，并在控制生物过程中发挥关键作用。植物具有与动物和原核生物不同的独特O-糖基化类型，它们通过调节转录以及介导定位和降解来调节分泌蛋白和核质蛋白的功能。由于存在数十种不同的O-聚糖类型、O-聚糖连接的蛋白质中广泛存在的羟脯氨酸（Hyp）、丝氨酸（Ser）和苏氨酸（Thr）残基，以及连接糖的可变连接模式，O-糖基化很复杂。O-糖基化通过影响多种生理过程，特异性地影响植物发育和环境适应性。本文综述了植物中蛋白质O-糖基化检测和功能的最新研究，并为植物发育和抗性的O-糖基化网络提供了一个框架。
