巴西非疟疾流行地区的疟疾和 COVID-19 合并感染。
Malaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil.
机构信息
Instituto Couto Maia, Salvador, BA, Brasil.
Instituto de Pesquisa Clínica Carlos Borborema, Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.
出版信息
Rev Soc Bras Med Trop. 2023 May 22;56:e05982022. doi: 10.1590/0037-8682-0598-2022. eCollection 2023.
Differential diagnosis of coronavirus disease 2019 (COVID-19) from other febrile diseases is one of several challenges imposed by the pandemic. We present a case of severe malaria and COVID-19 coinfection in a non-malaria-endemic region. A 44-year-old female with malaise, fever, hypotension, jaundice, and enlarged liver and spleen was admitted to the intensive care unit. Reverse transcription-quantitative PCR results for severe acute respiratory syndrome coronavirus 2 were positive. Rapid tests, microscopy, and quantitative PCR were positive for Plasmodium vivax. Cytokine storm profiles were identified. We could not determine whether the severe vivax malaria in our patient was triggered by COVID-19 coinfection.
2019 年冠状病毒病（COVID-19）与其他发热性疾病的鉴别诊断是大流行带来的挑战之一。我们报告了一例非疟疾流行地区的严重疟疾和 COVID-19 合并感染病例。一名 44 岁女性出现不适、发热、低血压、黄疸和肝脾肿大，被收入重症监护病房。严重急性呼吸综合征冠状病毒 2 的逆转录定量 PCR 结果为阳性。快速检测、显微镜检查和定量 PCR 均为间日疟原虫阳性。鉴定出细胞因子风暴谱。我们无法确定我们患者的严重间日疟是否由 COVID-19 合并感染引发。
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