Ettrich T J, Schuhbaur J S, Seufferlein T
Klinik für Innere Medizin I, Universitätsklinikum Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Deutschland.
Inn Med (Heidelb). 2023 Jun;64(6):546-559. doi: 10.1007/s00108-023-01516-y. Epub 2023 May 24.
The treatment of metastatic colorectal cancer (mCRC) has been considerably expanded and relevantly improved in recent years with new strategies, such as resection of liver and/or lung metastases, induction and maintenance treatment, the establishment of targeted therapies and molecularly defined strategies in defined subgroups. This article presents evidence-based treatment options and algorithms, with a focus on systemic treatment.
近年来,转移性结直肠癌(mCRC)的治疗有了显著扩展并得到相关改善,采用了新策略,如肝和/或肺转移灶切除术、诱导和维持治疗、靶向治疗的建立以及在特定亚组中采用分子定义策略。本文介绍了基于证据的治疗选择和算法,重点是全身治疗。