Department of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Surg Today. 2024 Feb;54(2):106-112. doi: 10.1007/s00595-023-02704-x. Epub 2023 May 24.
Defunctioning loop ileostomy has been reported to reduce symptomatic anastomotic leakage after rectal cancer surgery; however, stoma outlet obstruction (SOO) is a serious postileostomy complication. We, therefore, explored novel risk factors for SOO in defunctioning loop ileostomy after rectal cancer surgery.
This is a retrospective study that included 92 patients who underwent defunctioning loop ileostomy with rectal cancer surgery at our institution. Among them, 77 and 15 ileostomies were created at the right lower abdominal and umbilical sites, respectively. We defined the output volume as the maximum output volume the day before the onset of SOO or-for those without SOO-that was observed during hospitalization. Univariate and multivariate analyses were performed to evaluate risk factors for SOO.
SOO was observed in 24 cases, and the median onset was 6 days postoperatively. The stoma output volume in the SOO group was consistently higher than that in the non-SOO group. In the multivariate analysis, the rectus abdominis thickness (p < 0.01) and output volume (p < 0.01) were independent risk factors for SOO.
A high-output stoma may predict SOO in patients with defunctioning loop ileostomy for rectal cancer. Considering that SOO occurs even at umbilical sites with no rectus abdominis, a high-output stoma may trigger SOO primarily.
有报道称,预防性回肠造口术可降低直肠癌术后吻合口相关并发症的发生率,其中以症状性吻合口漏为主;但造口出口梗阻(SOO)是预防性回肠造口术后严重的并发症之一。本研究旨在探讨直肠癌术后预防性回肠造口术发生 SOO 的新的危险因素。
本研究为回顾性研究,共纳入 92 例行直肠癌根治术并行预防性回肠造口术的患者,其中右下腹造口 77 例,脐部造口 15 例。我们将造口输出量定义为发生 SOO 前一天的最大输出量或(对于未发生 SOO 的患者)住院期间观察到的最大输出量。我们进行了单因素和多因素分析,以评估 SOO 的危险因素。
24 例患者发生了 SOO,其中位发病时间为术后第 6 天。SOO 组的造口输出量始终高于非 SOO 组。多因素分析显示,腹直肌厚度(p<0.01)和输出量(p<0.01)是 SOO 的独立危险因素。
高输出量的造口可能是预测直肠癌预防性回肠造口术患者发生 SOO 的因素。考虑到即使在没有腹直肌的脐部也会发生 SOO,高输出量的造口可能是导致 SOO 的主要因素。