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酒精和物质使用障碍患者治疗期间规律体育活动与抑郁症状之间的关联

The Association Between Regular Physical Activity and Depressive Symptoms Among Patients in Treatment of Alcohol and Substance Use Disorders.

作者信息

Berger Endre, Bolstad Ingeborg, Lien Lars, Bramness Jørgen G

机构信息

Blue Cross East, Oslo, Norway.

Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Innlandet Hospital Trust, Brumunddal, Norway.

出版信息

Subst Abuse. 2023 May 19;17:11782218231175813. doi: 10.1177/11782218231175813. eCollection 2023.

Abstract

BACKGROUND

Alcohol and other substance use disorders and major depression often co-occur. A sedentary lifestyle is related to major depression and even moderate exercise may prevent and contribute to the treatment of depression. Studies have found an effect of physical activity on depression in alcohol and other substance use disorder patients even in clinical settings.

AIM

To investigate the relationship between level of physical activity and depressive symptoms over time in alcohol and substance use disorder inpatients.

METHODS

Eighty-nine substance use disorder inpatients were followed for 6 months during treatment. The International Physical Activity Questionnaire was used to categorize 3 groups of low, moderate, or high level of physical activity. In addition to background variables and alcohol and drug use measures, data on biometric measures and on sleep were gathered. Becks Depression Inventory version II (BDI-II) measured depressive symptoms. A multilevel logistic regression was used to analyze the longitudinal relationship between physical activity and depressive symptoms.

RESULTS

Most patients (57%) reported low activity, while 24% reported moderate and 19% high activity. Few changed their activity level during treatment. Moderate physical activity was related to lower score on BDI-II ( = .029). Level of physical activity was closely related to insomnia ( = .024). In the multivariate analysis the relationship between depressive symptoms and physical activity did not withstand the adjustment for insomnia. However, in the multilevel logistic regression higher physical activity was related to lower BDI-II score in a dose dependent manner.

CONCLUSIONS

Among these alcohol and other substance use disorders patients in treatment, there was a relationship between depressive symptoms and physical activity. The low level of physical activity identified among these patients was related to a high level of depressive symptoms. The level of depressive symptoms declined over time; but this change was not related to an increase in physical activity.

摘要

背景

酒精及其他物质使用障碍与重度抑郁症常常同时出现。久坐不动的生活方式与重度抑郁症有关,即使适度运动也可能预防抑郁症并有助于抑郁症的治疗。研究发现,即使在临床环境中,体育活动对酒精及其他物质使用障碍患者的抑郁症也有影响。

目的

调查酒精及物质使用障碍住院患者体育活动水平与抑郁症状随时间的关系。

方法

89名物质使用障碍住院患者在治疗期间被随访6个月。使用国际体力活动问卷将患者分为低、中、高体力活动水平三组。除了背景变量以及酒精和药物使用指标外,还收集了生物特征测量和睡眠数据。使用贝克抑郁量表第二版(BDI-II)测量抑郁症状。采用多水平逻辑回归分析体育活动与抑郁症状之间的纵向关系。

结果

大多数患者(57%)报告活动水平低,而24%报告中等活动水平,19%报告高活动水平。治疗期间很少有人改变其活动水平。中等体力活动与BDI-II得分较低相关(P = 0.029)。体力活动水平与失眠密切相关(P = 0.024)。在多变量分析中,抑郁症状与体育活动之间的关系在对失眠进行调整后不再成立。然而,在多水平逻辑回归中,较高的体力活动与较低的BDI-II得分呈剂量依赖性相关。

结论

在这些接受治疗的酒精及其他物质使用障碍患者中,抑郁症状与体育活动之间存在关联。这些患者中确定的低体力活动水平与高水平的抑郁症状相关。抑郁症状水平随时间下降;但这种变化与体力活动的增加无关。

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