Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility.
作者信息
Vierstraete Jeroen, Fieuws Charlotte, Creytens David, Van Dorpe Jo, Willaert Andy, Vral Anne, Claes Kathleen Bm
机构信息
Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University Hospital and Ghent University, 9000 Ghent, Belgium.
Department of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.
出版信息
Genes Dis. 2022 May 13;10(2):381-384. doi: 10.1016/j.gendis.2022.04.023. eCollection 2023 Mar.
Abstract
摘要
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本文引用的文献
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Zebrafish Cancer Predisposition Models.斑马鱼癌症易感性模型
Front Cell Dev Biol. 2021 Apr 27;9:660069. doi: 10.3389/fcell.2021.660069. eCollection 2021.
2
ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.ATM 和 PRDM9 在减数分裂过程中调节 SPO11 结合的重组中间体。
Nat Commun. 2020 Feb 12;11(1):857. doi: 10.1038/s41467-020-14654-w.
3
Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility.多重 CRISPR/Cas9 介导的斑马鱼 19 个范可尼贫血通路基因敲除揭示了它们在生长、性发育和生育中的作用。
PLoS Genet. 2018 Dec 12;14(12):e1007821. doi: 10.1371/journal.pgen.1007821. eCollection 2018 Dec.
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deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish.缺乏会导致广泛的肿瘤谱，并增加斑马鱼胚胎横纹肌肉瘤的转移。
Elife. 2018 Sep 7;7:e37202. doi: 10.7554/eLife.37202.
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brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis.BRCA2 在斑马鱼卵巢发育、精子发生和肿瘤发生中的作用。
Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19350-5. doi: 10.1073/pnas.1011630107. Epub 2010 Oct 25.
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