Merashli Mira, Ames Paul Rj
Department of Internal Medicine, Rheumatology Division, American University of Beirut, Beirut, Lebanon.
CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisboa, Portugal.
Mediterr J Rheumatol. 2023 Feb 21;34(1):66-70. doi: 10.31138/mjr.34.1.66. eCollection 2023 Mar.
the prevalence of venous thromboembolism (VTE) in Behcet's disease (BD) is around 40%, though recognition of BD in a thrombosis clinic has been poorly addressed.
to evaluate the prevalence of signs and symptoms leading to the diagnosis of BD in a thrombosis clinic compared to patients attending a general haematology clinic and to healthy controls. Design: cross-sectional case-double control anonymous questionnaire survey. Participants: consecutive patients with spontaneous VTE (n=97) attending a thrombosis clinic, consecutive patients from a general haematology (GH) clinic (n=89) and controls (CTR).
BD was diagnosed in 1.03% of VTE participants, in 2.2% of GH participants and in 1.2% of healthy CTR. Exhaustion was more common reported in participants from the VTE group (15.6%) than in those from the GH group (10.3%) and from the healthy CTR (3%) (p=0.06); the sum of signs and symptoms of BD clustered in the VTE group (89.5%) compared to the GH (72.4%) and the CTR (59.7%) (p<0.0001).
BD may be diagnosed in 1 every 100 patients with VTE attending a thrombosis clinic and in 2 every 100 patients attending a GH clinic: awareness must be raised not to under-diagnose or misdiagnose BD in these settings as management of VTE in BD deviates from the norm.
白塞病（BD）患者静脉血栓栓塞症（VTE）的患病率约为40%，尽管在血栓形成门诊对白塞病的识别情况较差。
与普通血液科门诊患者及健康对照相比，评估血栓形成门诊中导致白塞病诊断的体征和症状的患病率。设计：横断面病例-双对照匿名问卷调查。参与者：血栓形成门诊的连续自发性VTE患者（n=97）、普通血液科（GH）门诊的连续患者（n=89）及对照（CTR）。
VTE参与者中1.03%被诊断为白塞病，GH参与者中为2.2%，健康对照中为1.2%。VTE组参与者报告疲劳的情况（15.6%）比GH组（10.3%）和健康对照（3%）更常见（p=0.06）；与GH组（72.4%）和CTR组（59.7%）相比，白塞病的体征和症状总和在VTE组更为集中（89.5%）（p<0.0001）。
在血栓形成门诊就诊的每100例VTE患者中可能有1例被诊断为白塞病，在GH门诊就诊的每100例患者中有2例：必须提高认识，避免在这些情况下对白塞病诊断不足或误诊，因为白塞病中VTE的管理与常规不同。
