Chávez-Oliveros Mireya, Flores-Lázaro Julio César, Meza Haydee Durán, Ramírez-Burgos Wendy
Instituto Nacional de Neurología y Neurocirugía, Departamento de Neuropsicología, Ciudad de México, Mexico.
Secretaria de Salud de Mexico, Hospital Psiquiátrico Infantil Dr. Juan N. Navarro, Servicios de Atención Psiquiátrica, Ciudad de México, Mexico.
Dement Neuropsychol. 2023 Feb 6;17:e20220027. doi: 10.1590/1980-5764-DN-2022-0027. eCollection 2023.
Motor-action verbs (MAVs) production and comprehension are compromised in patients with Parkinson's disease (PD).
The aim of this study was to characterize the sequential production of three subtypes of MAVs in PD patients: whole body (e.g., ), specific body part (e.g., ), and instrumental (e.g., ). This study also aimed to identify the production characteristics for each of the two main phases in fluency performance: selection (initial abundant item production) and retrieval (more paced and scarce production).
This study involved a group of 20 nondemented, on-medication PD patients, with an average age of 66.59 years (standard deviation = 4.13), and a comparison group (CG) of 20 normal elderly individuals, matched by years of education and controlled for cognitive performance and depression. Both groups performed a classical verb fluency task. Sequential word-by-word analyses were conducted.
Significant differences were found at the initial production of whole-body MAVs and the overall production of instrumental verbs (both measures were lower in the PD group). A repeated-measures analysis of variance confirmed the linear CG performance and the quadratic PD performance.
PD patients present altered production of whole-body and instrumental MAVs. This proposal for the semantic sequential analysis of motor verbs deserves further investigation, as a new methodology for the evaluation of fluency performance in motor-related disease.
帕金森病（PD）患者的动作动词（MAV）生成和理解能力受损。
本研究旨在描述PD患者中三种MAV亚型的顺序生成情况：全身动作（如 ）、特定身体部位动作（如 ）和工具性动作（如 ）。本研究还旨在确定流畅性表现两个主要阶段中每个阶段的生成特征：选择（最初丰富的词汇生成）和检索（节奏较慢且词汇量较少的生成）。
本研究纳入了一组20名未患痴呆症、正在服药的PD患者，平均年龄为66.59岁（标准差 = 4.13），以及一个由20名正常老年人组成的对照组（CG），两组在受教育年限上匹配，并对认知表现和抑郁情况进行了控制。两组均执行经典的动词流畅性任务，并进行逐词顺序分析。
在全身MAV的初始生成和工具性动词的总体生成方面发现了显著差异（PD组的这两项指标均较低）。重复测量方差分析证实了CG组的线性表现和PD组的二次函数表现。
PD患者全身动作和工具性动作的MAV生成存在改变。作为一种评估运动相关疾病流畅性表现的新方法，这种对动作动词进行语义顺序分析的提议值得进一步研究。
