College of Chemistry, Institute of Analytical Chemistry for Life Science, Henan Joint International Research Laboratory of Green Construction of Functional Molecules and Their Bioanalytical Applications, Zhengzhou University, Zhengzhou, 450001, PR China.
School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450001, PR China.
Anal Chim Acta. 2023 Jul 4;1263:341245. doi: 10.1016/j.aca.2023.341245. Epub 2023 Apr 22.
Nitrite (NO) is extensively found in the daily dietary environment. However, consuming too much NO can pose serious health risks. Thus, we designed a NO-activated ratiometric upconversion luminescence (UCL) nanosensor which could realize NO detection via the inner filter effect (IFE) between NO-sensitive carbon dots (CDs) and upconversion nanoparticles (UCNPs). Due to the exceptional optical properties of UCNPs and the remarkable selectivity of CDs, the UCL nanosensor exhibited a good response to NO. By taking advantage of NIR excitation and ratiometric detection signal, the UCL nanosensor could eliminate the autofluorescence thereby increasing the detection accuracy effectively. Additionally, the UCL nanosensor proved successful in detecting NO quantitatively in actual samples. The UCL nanosensor provides a simple as well as sensitive sensing strategy for NO detection and analysis, which is anticipated to extend the utilization of upconversion detection in food safety.
亚硝酸盐（NO）广泛存在于日常饮食环境中。然而，摄入过多的 NO 会对健康造成严重的风险。因此，我们设计了一种 NO 激活的比率型上转换发光（UCL）纳米传感器，它可以通过对 NO 敏感的碳点（CDs）和上转换纳米粒子（UCNPs）之间的内滤效应（IFE）来实现对 NO 的检测。由于 UCNPs 的独特光学性质和 CDs 的显著选择性，UCL 纳米传感器对 NO 表现出了良好的响应。通过利用近红外激发和比率检测信号，UCL 纳米传感器可以有效地消除自发荧光，从而提高检测的准确性。此外，该 UCL 纳米传感器在实际样品中成功地对 NO 进行了定量检测。该 UCL 纳米传感器为 NO 的检测和分析提供了一种简单而灵敏的传感策略，有望扩展上转换检测在食品安全中的应用。
