Akinaga Chieko, Kawashima Shingo, Suzuki Yuji, Matsumoto Masako, Nakajima Yoshiki
Department of Anesthesiology and Intensive Care Medicine, Hamamatsu University Hospital, 1-20-1 Handayama, Higashi-Ku, Hamamatsu-Shi, Shizuoka, 431-3192, Japan.
Department of Obstetrics and Gynecology, Hamamatsu University Hospital, Hamamatsu, Japan.
JA Clin Rep. 2023 May 25;9(1):30. doi: 10.1186/s40981-023-00623-x.
Perinatal management of congenital platelet dysfunction represents a challenge. One of the major concerns is whether neuraxial anesthesia can be applicable for cesarean delivery. We present a patient with thrombasthenia who underwent emergency cesarean delivery.
A 34-year-old primipara was diagnosed with autosomal dominant thrombasthenia, which was not classified as any known type. A thorough examination revealed that adenosine diphosphate aggregation and collagen aggregation were suppressed. Platelet mapping of viscoelastic testing was used to observe the trajectory of platelet function during pregnancy, which was found to be normal to hypercoagulable until 38 weeks of gestation. On the basis of the results of testing and physiological status, we commenced spinal anesthesia and avoided prophylactic platelet transfusion.
The platelet mapping of viscoelastic testing was rapid and simple, allowing repeated examinations. We could choose the appropriate anesthesia method and determine the necessity of blood transfusion for a pregnant patient with thrombasthenia.
先天性血小板功能障碍的围产期管理是一项挑战。主要担忧之一是神经轴索麻醉是否适用于剖宫产。我们报告一例血小板无力症患者接受急诊剖宫产的情况。
一名34岁初产妇被诊断为常染色体显性血小板无力症,不属于任何已知类型。全面检查显示二磷酸腺苷聚集和胶原聚集均受抑制。采用粘弹性检测的血小板功能图谱观察孕期血小板功能轨迹,发现直至妊娠38周均正常至高凝状态。根据检测结果和生理状况,我们实施了脊髓麻醉并避免预防性血小板输注。
粘弹性检测的血小板功能图谱快速且简便,允许重复检查。我们能够为血小板无力症的孕妇选择合适的麻醉方法并确定输血的必要性。