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微脉冲经巩膜睫状体光凝术的临床结果:葡萄牙患者两年的经验

Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation: 2 Years of Experience in Portuguese Eyes.

作者信息

Basto Rita C, Almeida Júlio, Roque Joana N, Henriques Susana P, Gonçalves Ana S, Vaz Fernando T, Carvalho Helena, Prieto Isabel

机构信息

Department of Surgery, Ophthalmology Service, Unidade Local De Saúde Matosinhos, Hospital Pedro Hispano, Matosinhos, Portugal.

Department of Ophthalmology, Professor Doutor Fernando Fonseca Hospital, Lisboa, Portugal.

出版信息

J Curr Glaucoma Pract. 2023 Jan-Mar;17(1):30-36. doi: 10.5005/jp-journals-10078-1395.

Abstract

AIM

This study evaluates the safety and efficacy of micropulse transscleral cyclophotocoagulation (MPTSCPC) in glaucoma patients, with standard parameters, over a 24-month period.

METHODS

Retrospective analysis of 61 eyes undergoing MPTSCPC from January 2018 to December 2020 was carried out. Patients received 160 seconds of laser, with settings of 2000 mW/cm and a duty cycle of 31.3%.

RESULTS

A total of 61 eyes were included, arranged in an age distribution of 73.9 ± 10.8 years. The most frequent diagnosis was primary open-angle glaucoma (POAG), with a mean best-corrected visual acuity (BCVA) of 5/10 in the Snellen Visual chart. Around 37.7% of the eyes had undergone at least one glaucoma filtration surgery prior to MPTSCPC. The mean pretreatment intraocular pressure (IOP) was 24.9 ± 8.6 mm Hg. Except for the contrast at 24 months, at every other follow-up visit, there was a significant reduction ( ≤ 0.001) in IOP and in the number of topical drugs required to control IOP, from four (baseline) to three, with oral acetazolamide suspension in most cases. The total success rate (absolute and clinical successes combined) was 81.9% after 1 year of the treatment. There was no drop in visual acuity or cases of serious complications. There is a positive and significant correlation between prior glaucoma surgery and the need for reinterventions ( = 0.028).

CONCLUSIONS

Micropulse transscleral cyclophotocoagulation (MPTSCPC) is an effective and safe procedure for reducing IOP within a broad spectrum of glaucoma patients. Additional studies are needed to confirm the current indications, widen their scope, and determine the optimal treatment settings on an individual basis.

HOW TO CITE THIS ARTICLE

Basto RC, Almeida J, Roque JN, Clinical Outcomes of Micropulse Transscleral Cyclophotocoagulation: 2 Years of Experience in Portuguese Eyes. J Curr Glaucoma Pract 2023;17(1):30-36.

摘要

目的

本研究评估在24个月期间,采用标准参数的微脉冲经巩膜睫状体光凝术(MPTSCPC)对青光眼患者的安全性和有效性。

方法

对2018年1月至2020年12月期间接受MPTSCPC的61只眼进行回顾性分析。患者接受160秒的激光治疗,参数设置为2000 mW/cm,占空比为31.3%。

结果

共纳入61只眼,年龄分布为73.9±10.8岁。最常见的诊断是原发性开角型青光眼(POAG),在斯内伦视力表中的平均最佳矫正视力(BCVA)为5/10。约37.7%的眼睛在接受MPTSCPC之前至少接受过一次青光眼滤过手术。术前平均眼压(IOP)为24.9±8.6 mmHg。除24个月时的对比情况外,在其他每次随访中,眼压以及控制眼压所需的局部用药数量均有显著降低(≤0.001),从4种(基线)降至3种,大多数情况下联合口服乙酰唑胺混悬液。治疗1年后,总成功率(绝对成功和临床成功合并)为81.9%。视力没有下降,也没有严重并发症病例。既往青光眼手术与再次干预的必要性之间存在正相关且具有显著性(=0.028)。

结论

微脉冲经巩膜睫状体光凝术(MPTSCPC)是一种在广泛的青光眼患者中降低眼压的有效且安全的方法。需要进一步研究以确认当前的适应证,扩大其范围,并根据个体情况确定最佳治疗参数。

如何引用本文

巴斯托RC,阿尔梅达J,罗克JN,微脉冲经巩膜睫状体光凝术的临床结果:葡萄牙患者的2年经验。《当代青光眼实践杂志》2023;17(1):30 - 36。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bc6/10203329/34aa575348fb/jocgp-17-30-g001.jpg

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