Alasqah Abdulrahman Abdullah, Alonazi Raghad Harran, Alamoudi Shefa Abdullah, Alotaiby Nayef Diyab
Department of Research, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Clin Ophthalmol. 2025 Jul 17;19:2373-2381. doi: 10.2147/OPTH.S519777. eCollection 2025.
To compare the efficacy, safety and outcomes of micropulse cyclophotocoagulation (MP-CPC) to ultrasound cycloplasty (UCP) in patients referred to a tertiary eye care center in Riyadh, Saudi Arabia.
A retrospective study evaluated data from patients who had undergone MP-CPC or UCP from January 2017 to October 2023. Patients who lost to follow up and patients with incomplete medical reports were excluded from the study. Data was collected for day 1, 2nd week, 1 month and 3, 6, and 12 months postoperatively. At each visit, data was collected on intraocular pressure (IOP), corrected distance visual acuity (CDVA), medications and possible complications. Data was compared between groups. P<0.05 was considered statistically significant.
Out of 139 eyes, 65 underwent UCP, and 74 underwent MP-CPC. IOP in the UCP group decreased from 29.67±9.82 mmHg preoperatively to 21.00±6.78 mmHg at one year postoperatively and in the MP-CPC group, IOP decreased from 28.44±9.46 mmHg to 20.41±8.77 mmHg respectively. In the UCP group, at the 1-year follow-up, vision remained unchanged from the preoperative levels in 6 eyes (27.3%), while 2 eyes (9.1%) lost 1 line of vision, and 8 eyes (36.4%) experienced a loss of ≥2 lines. In the MP-CPC group, at the 1-year follow-up, vision remained unchanged in 24 eyes (43.6%), 2 eyes (3.6%) lost 1 line, and 20 eyes (36.4%) had a loss of ≥2 lines. The number of antiglaucoma medications at 1 year postoperatively did not differ between groups. The qualified success rate at 1 year was similar between groups.
Both UCP and MP-CPC are safe and effective for reducing IOP in refractory glaucoma, with similar reductions observed between the two techniques. Visual outcomes and qualified success rates were comparable between UCP and MP-CPC.
在沙特阿拉伯利雅得一家三级眼科护理中心就诊的患者中,比较微脉冲睫状体光凝术(MP-CPC)与超声睫状体成形术(UCP)的疗效、安全性和治疗结果。
一项回顾性研究评估了2017年1月至2023年10月期间接受MP-CPC或UCP治疗的患者的数据。失访患者和病历报告不完整的患者被排除在研究之外。收集术后第1天、第2周、1个月以及3、6和12个月的数据。每次就诊时,收集眼压(IOP)、矫正远视力(CDVA)、用药情况和可能出现的并发症的数据。对两组数据进行比较。P<0.05被认为具有统计学意义。
在139只眼中,65只接受了UCP,74只接受了MP-CPC。UCP组的眼压从术前的29.67±9.82 mmHg降至术后1年的21.00±6.78 mmHg,MP-CPC组的眼压分别从28.44±9.46 mmHg降至20.41±8.77 mmHg。在UCP组,1年随访时,6只眼(27.3%)的视力与术前水平相比无变化,2只眼(9.1%)视力下降1行,8只眼(36.4%)视力下降≥2行。在MP-CPC组,1年随访时,24只眼(43.6%)视力无变化,2只眼(3.6%)视力下降1行,20只眼(36.4%)视力下降≥2行。术后1年两组抗青光眼药物的使用数量无差异。两组1年时的合格成功率相似。
UCP和MP-CPC在降低难治性青光眼眼压方面均安全有效,两种技术降低眼压的效果相似。UCP和MP-CPC的视觉效果和合格成功率相当。