抗神经元自身抗体在精神分裂症谱系障碍中诱发副肿瘤综合征：病例报告
Antineuronal autoantibodies induced paraneoplasic syndrome in schizophrenia spectrum disorders: case report.
作者信息
Jaballah Fares, Ben Hamed Nouha, Hamzaoui Sayma, Ayadi Mohamed A, Zgueb Yosra, Jomli Rabaa
机构信息
Avicenna (A) Department, Razi Hospital, Tunis-El Manar University.
Carcinoligical Surgery Department, Salah Azaiez Hospital, Tunis-El Manar University, Tunis, Tunisia.
出版信息
Ann Med Surg (Lond). 2023 Apr 11;85(5):2046-2048. doi: 10.1097/MS9.0000000000000540. eCollection 2023 May.
UNLABELLED
Secondary psychiatric symptoms are usually suspected when there is an atypical presentation of the symptoms or a lack of response to psychotropic medication.
CASE PRESENTATION
Our case is about a woman aged 62 years old, with a history of mental disorder who presented psychiatric symptomatology after years of being stabilized by antipsychotics. She was later investigated due to a mass in her breast. Carcinoma was diagnosed, and her psychiatric symptomatology was resolved after the tumerectomy.
DISCUSSION
The therapeutic difficulty is the major problem of psychic disorders in the context of paraneoplastic syndrome. Several literature review have suggested a relationship between schizophrenia and antineuronal antibodies in the context of paraneoplastic syndrome. Treating the tumor can solve psychiatric symptoms better than psychotic treatment.
CONCLUSIONS
The aim of our study is to highlight the importance of a complete medical evaluation to identify the psychiatric presentations of organic disorders associated with psychiatric manifestation and to ensure an early diagnosis.
未标注
当症状表现不典型或对抗精神病药物缺乏反应时，通常会怀疑存在继发性精神症状。
病例介绍
我们的病例是一位62岁的女性，有精神障碍病史，在多年使用抗精神病药物病情稳定后出现了精神症状。后来她因乳房肿块接受检查。诊断为癌症，肿瘤切除术后她的精神症状消失。
讨论
治疗困难是副肿瘤综合征背景下精神障碍的主要问题。几项文献综述表明，在副肿瘤综合征背景下，精神分裂症与抗神经元抗体之间存在关联。治疗肿瘤比治疗精神疾病能更好地解决精神症状。
结论
我们研究的目的是强调全面医学评估的重要性，以识别与精神表现相关的器质性疾病的精神症状，并确保早期诊断。
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