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《2023年丙型肝炎指南更新:美国肝病研究学会-美国感染病学会关于丙型肝炎病毒感染检测、管理及治疗的建议》

Hepatitis C Guidance 2023 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection.

作者信息

Bhattacharya Debika, Aronsohn Andrew, Price Jennifer, Lo Re Vincent

机构信息

Department of Medicine, Division of Infectious Diseases, David Geffen School of Medicine at UCLA.

Department of Medicine, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago.

出版信息

Clin Infect Dis. 2023 May 25. doi: 10.1093/cid/ciad319.

Abstract

The Infectious Diseases Society of America and the American Association for the Study of Liver Diseases have collaboratively developed evidence-based guidance regarding the diagnosis, management, and treatment of hepatitis C virus (HCV) infection since 2013. A panel of clinicians and investigators with extensive infectious diseases or hepatology expertise specific to HCV infection periodically review evidence from the field and update existing recommendations or introduce new recommendations as evidence warrants. This update focuses on changes to the guidance since the previous 2020 published update, including ongoing emphasis on recommended universal screening; management recommendations for incomplete treatment adherence; expanded eligibility for simplified chronic HCV infection treatment in adults with minimal monitoring; updated treatment and retreatment recommendations for children as young as 3 years old; management and treatment recommendations in the transplantation setting; and screening, treatment, and management recommendations for unique and key populations.

摘要

自2013年以来,美国传染病学会和美国肝病研究协会就丙型肝炎病毒(HCV)感染的诊断、管理和治疗共同制定了循证指南。一个由具有HCV感染相关广泛传染病或肝病专业知识的临床医生和研究人员组成的小组定期审查该领域的证据,并根据证据需要更新现有建议或提出新建议。本次更新重点关注自上一次2020年发布的更新以来指南的变化,包括持续强调推荐的普遍筛查;不完全治疗依从性的管理建议;扩大了对监测要求最低的成年慢性HCV感染患者进行简化治疗的资格;更新了对年仅3岁儿童的治疗和再治疗建议;移植环境中的管理和治疗建议;以及针对特殊和关键人群的筛查、治疗和管理建议。

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