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伯恩病毒(拟归披膜病毒科)的形态发生

Morphogenesis of Berne virus (proposed family Toroviridae).

作者信息

Weiss M, Horzinek M C

出版信息

J Gen Virol. 1986 Jul;67 ( Pt 7):1305-14. doi: 10.1099/0022-1317-67-7-1305.

DOI:10.1099/0022-1317-67-7-1305
PMID:3723110
Abstract

In equine dermis cells infected with Berne virus particles were first detected 10 h after infection. Virions were encountered in all parts of the Golgi system and, infrequently, in the rough endoplasmic reticulum. A unique form of budding of preassembled rigid tubular nucleocapsids was demonstrated. Masses of tubular nucleocapsids of a lesser diameter and electron density were prominent in the cytoplasm and the nucleus of infected cells. Within the Golgi system and cytoplasmic cisternae virions appeared as straight or slightly curved rods. Extremely long, aberrant virions (250 nm) were occasionally seen. The proper torovirion morphology was observed in extracellular particles and in vacuoles near the cell surface.

摘要

在感染伯尔尼病毒颗粒的马真皮细胞中,感染后10小时首次检测到病毒颗粒。在高尔基体系统的所有部位均发现有病毒粒子,偶尔也在粗面内质网中发现。证明了预组装的刚性管状核衣壳的一种独特出芽形式。直径较小且电子密度较低的管状核衣壳团块在受感染细胞的细胞质和细胞核中很突出。在高尔基体系统和细胞质池中,病毒粒子呈直杆状或微弯杆状。偶尔可见极长的异常病毒粒子(250纳米)。在细胞外颗粒和细胞表面附近的液泡中观察到了正确的环曲病毒形态。

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