School of Public and Community Health Sciences, University of Montana, Missoula, USA.
Center for Population Health Research, University of Montana, Missoula, USA.
BMC Geriatr. 2023 May 25;23(1):328. doi: 10.1186/s12877-023-03890-6.
Although slow gait speed is an established risk factor for falls, few studies have evaluated change in gait speed as a predictor of falls or considered variability in effects by cognitive status. Change in gait speed may be a more useful metric because of its potential to identify decline in function. In addition, older adults with mild cognitive impairment are at an elevated risk of falls. The purpose of this research was to quantify the association between 12-month change in gait speed and falls in the subsequent 6 months among older adults with and without mild cognitive impairment.
Falls were self-reported every six months, and gait speed was ascertained annually among 2,776 participants in the Ginkgo Evaluation of Memory Study (2000-2008). Adjusted Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for fall risk relative to a 12-month change in gait speed.
Slowing gait speed over 12 months was associated with increased risk of one or more falls (HR:1.13; 95% CI: 1.02 to 1.25) and multiple falls (HR:1.44; 95% CI: 1.18 to 1.75). Quickening gait speed was not associated with risk of one or more falls (HR 0.97; 95% CI: 0.87 to 1.08) or multiple falls (HR 1.04; 95% CI: 0.84 to 1.28), relative to those with a less than 0.10 m/s change in gait speed. Associations did not vary by cognitive status (p = 0.95 all falls, 0.25 multiple falls).
Decline in gait speed over 12 months is associated with an increased likelihood of falls among community-dwelling older adults, regardless of cognitive status. Routine checks of gait speed at outpatient visits may be warranted as a means to focus fall risk reduction efforts.
虽然步态缓慢是跌倒的既定危险因素,但很少有研究评估步态速度变化作为跌倒的预测因子,也没有考虑认知状态对效应的可变性。步态速度的变化可能是一种更有用的指标,因为它有可能识别功能下降。此外,轻度认知障碍的老年人跌倒风险较高。本研究的目的是量化步态速度在 12 个月内的变化与老年人在随后 6 个月内跌倒之间的关系,包括有和没有轻度认知障碍的老年人。
在银杏评估记忆研究(2000-2008 年)中,每 6 个月报告一次跌倒情况,每年确定 2776 名参与者的步态速度。使用调整后的 Cox 比例风险模型估计相对于 12 个月的步态速度变化,跌倒风险的风险比(HR)和 95%置信区间(CI)。
12 个月内步态速度减慢与跌倒风险增加相关(HR:1.13;95%CI:1.02 至 1.25)和多次跌倒(HR:1.44;95%CI:1.18 至 1.75)。步态速度加快与一次或多次跌倒(HR 0.97;95%CI:0.87 至 1.08)或多次跌倒(HR 1.04;95%CI:0.84 至 1.28)的风险无关,相对于步态速度变化小于 0.10 m/s 的患者。认知状态对这些关联没有影响(所有跌倒的 p = 0.95,多次跌倒的 p = 0.25)。
在社区居住的老年人中,12 个月内步态速度下降与跌倒的可能性增加相关,无论认知状态如何。在门诊就诊时常规检查步态速度可能是降低跌倒风险的一种手段。