Lamba P A, Bhalla J S, Mullick D N
J Pediatr Ophthalmol Strabismus. 1986 May-Jun;23(3):123-5. doi: 10.3928/0191-3913-19860501-06.
Forty-eight children with tubercular meningitis were observed and followed up for development of ocular sequelae over a period of four months. Commonest ocular abnormality encountered in this condition was optic disc change (62%) of which papillitis was the most frequent. The incidence of pupillary change and cranial nerve paralysis was seen to be 48% and 28% respectively. Anisocoria and mydriasis were commonly observed pupillary changes. The third cranial nerve was the most frequent nerve involved in this condition. It was observed that patients who had high CSF protein content (greater than 75 mg%) showed more chances of development of primary optic atrophy (P value 0.001). Choroidal tubercle and papilledema were found to be signs of grave prognostic significance.
对48例结核性脑膜炎患儿进行了观察，并在4个月的时间里随访其眼部后遗症的发展情况。在这种情况下最常见的眼部异常是视盘改变（62%），其中乳头炎最为常见。瞳孔改变和脑神经麻痹的发生率分别为48%和28%。不等大瞳孔和瞳孔散大是常见的瞳孔改变。第三脑神经是这种情况下最常受累的神经。观察发现，脑脊液蛋白含量高（大于75mg%）的患者发生原发性视神经萎缩的可能性更大（P值0.001）。脉络膜结核和视乳头水肿被发现是具有严重预后意义的体征。
