Buras R R, Jacir N N, Anderson K D
J Pediatr Surg. 1986 Jun;21(6):545-7. doi: 10.1016/s0022-3468(86)80230-5.
A study was undertaken to determine whether reflux could be reduced or prevented by creation of a nipple valve at the distal end of a reversed gastric tube. The gastric tube was constructed in standard fashion in six adult dogs. The tube was placed through a substernal tunnel to a cutaneous ostomy in the neck. An antireflux valve was then created by invaginating the lower end of the tube into the gastric remnant. The following observations were made before and after creation of the valve: (1) gastric distending pressure required to produce efflux of saline from the ostomy; (2) manometric pressure at the stomach-tube junction; and (3) 2-hour pH monitoring within the tube after acid infusion into the stomach. The valve shortened the gastric tube by 2.0 to 2.5 cm. It did not obstruct antegrade flow of saline. Prior to creation of the valve, reflux of saline out of the cutaneous ostomy occurred at an average pressure of 62 cm H2O (range 25 to 80). The antireflux procedure prevented reflux with distending pressures up to 200 cm H2O. Manometry revealed an average pressure of 18 cm H2O (range 5 to 25) at the lower end of the tube before creation of the valve. The antireflux procedure raised this high pressure zone to 60 cm H2O (Range 50 to 65) (P less than 0.05). Spontaneous reflux was rarely observed in the anesthetized dog when acid was infused into the stomach and the pH was monitored in the gastric tube. Acid reflux could easily be produced by application of minimal manual pressure to the closed abdomen.(ABSTRACT TRUNCATED AT 250 WORDS)
开展了一项研究,以确定通过在倒置胃管的远端创建乳头瓣是否可以减少或预防反流。用标准方式在6只成年犬身上构建胃管。将该管通过胸骨后隧道放置到颈部的皮肤造口处。然后通过将管的下端内翻到胃残端来创建一个抗反流瓣。在创建瓣膜前后进行了以下观察:(1)从造口产生盐水流出所需的胃扩张压力;(2)胃管连接处的测压压力;以及(3)向胃内注入酸后在管内进行2小时的pH监测。瓣膜使胃管缩短了2.0至2.5厘米。它没有阻碍盐水的顺行流动。在创建瓣膜之前,盐水从皮肤造口反流的平均压力为62厘米水柱(范围为25至80)。抗反流手术可防止压力高达200厘米水柱时的反流。测压显示在创建瓣膜之前管下端的平均压力为18厘米水柱(范围为5至25)。抗反流手术将这个高压区提高到60厘米水柱(范围为50至65)(P小于0.05)。当向胃内注入酸并在胃管中监测pH值时,在麻醉的犬中很少观察到自发反流。通过对闭合的腹部施加最小的手动压力很容易产生酸反流。(摘要截取自250字)