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腹膜透析导管尖端设计对技术生存的影响:一项回顾性观察研究。

The Influence of Peritoneal Dialysis Catheter Tip Design on Technique Survival: A Retrospective Observational Study.

作者信息

Singh Vishal, Mishra Satish C, Singh Pulkit, Rout Binod B

机构信息

Department of Medicine, Division of Nephrology, 7 Air Force Hospital, Kanpur Cantt, Uttar Pradesh, India.

Division of Cardiology, Army Institute of Cardiothoracic Sciences (AICTS), Pune, Maharashtra, India.

出版信息

Indian J Nephrol. 2023 Mar-Apr;33(2):119-124. doi: 10.4103/ijn.ijn_158_21. Epub 2023 Feb 20.

Abstract

INTRODUCTION

The clinical practice guidelines for peritoneal access state that no particular peritoneal dialysis catheter (PDC) type has been proven superior to another. We present our experience with the use of different PDC tip designs.

METHOD

The study is a retrospective, real-world, observational, outcome analysis correlating the PDC tip design (straight vs. coiled-tip) and technique survival. The primary outcome was technique survival, and the secondary outcome included catheter migration and infectious complications.

RESULT

A total of 50 PDC (28 coiled-tip and 22 straight-tip) were implanted between March 2017 and April 2019 by using a guided percutaneous approach. The 1-month and 1-year technique survival in the coiled-tip PDC was 96.4% and 92.8%, respectively. Of the two coiled-tip catheters lost, one was a consequence of the patient having undergone live related kidney transplantation. The corresponding 1-month and 1-year technique survival with straight-tip PDC was 86.4% and 77.3%, respectively. When compared to straight-tip PDC, the use of coiled-tip PDC was associated with fewer early migration (3.6% vs. 31.8%; odds ratio (OR): 12.6; 95% confidence interval (CI): 1.41-112.39; = 0.02) and a trend toward favorable 1-year technique survival ( = 0.07; numbers needed to treat = 11). Therapy-related complications noted in the study included peri-catheter leak and PD peritonitis. The PD peritonitis rate in the coiled-tip and straight-tip group was 0.14 and 0.11 events per patient year, respectively.

CONCLUSION

The use of coiled-tip PDC, when placed using a guided percutaneous approach, reduces early catheter migration and shows a trend toward favorable long-term technique survival.

摘要

引言

腹膜置管临床实践指南指出,尚无证据表明某种特定类型的腹膜透析导管(PDC)优于其他类型。我们介绍了使用不同PDC尖端设计的经验。

方法

本研究是一项回顾性、基于实际情况的观察性结局分析,将PDC尖端设计(直型与卷曲型)与技术存活情况相关联。主要结局是技术存活,次要结局包括导管移位和感染并发症。

结果

2017年3月至2019年4月期间,采用引导下经皮穿刺方法共植入50根PDC(28根卷曲型尖端和22根直型尖端)。卷曲型尖端PDC的1个月和1年技术存活率分别为96.4%和92.8%。在丢失的两根卷曲型尖端导管中,一根是由于患者接受了活体亲属肾移植。直型尖端PDC相应的1个月和1年技术存活率分别为86.4%和77.3%。与直型尖端PDC相比,使用卷曲型尖端PDC可减少早期移位(3.6%对31.8%;优势比(OR):12.6;95%置信区间(CI):1.41 - 112.39;P = 0.02),且1年技术存活有改善趋势(P = 0.07;需治疗人数 = 11)。研究中记录的与治疗相关的并发症包括导管周围渗漏和腹膜透析相关性腹膜炎。卷曲型尖端组和直型尖端组的腹膜透析相关性腹膜炎发生率分别为每位患者每年0.14次和0.11次。

结论

采用引导下经皮穿刺方法放置卷曲型尖端PDC可减少早期导管移位,并显示出长期技术存活改善的趋势。

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