Abdul Rashid Anna M, Bidin Mohamad Z, Lim Christopher T S
Department of Medicine, Level 3, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Indian J Nephrol. 2022 Jul-Aug;32(4):307-311. doi: 10.4103/ijn.ijn_176_21. Epub 2022 Jul 16.
Despite improvements in insertion techniques and catheter designs, catheter malfunction and infection pose a great source of morbidity and limitation to adequate dialysis. The two most used peritoneal dialysis (PD) catheters are the coiled and straight PD catheters. Existing studies show conflicting results.
This study aims to look at the clinical outcomes and mortality between the two catheter types. This study was designed as an ambidirectional cohort study. A total of 126 patients undergoing PD, with 75 receiving the straight PD catheter and 51 receiving the coiled PD catheter, participated in the study. The primary outcome was catheter survival, and the secondary outcomes included PD failure, catheter-related infections, and all-cause mortality.
In the coiled catheter group, 30 (40%) patients had catheter malfunction, whereas the straight catheter group had 15 (29.4%) patients catheter malfunction. However, the survival functions represented by the Kaplan-Meier survival curve did not show any statistical significance ( = 0.659). In the coiled PD catheter group, 13 (17.3%) had PD failure, which was comparable with the straight PD catheter group of nine (17.6%) cases ( = 1.000). The catheter-related infections are similar in both groups. The mortality between two groups was also similar ( = 0.777).
There is no difference in outcomes between the coiled and straight PD catheters.
尽管在置管技术和导管设计方面有所改进,但导管故障和感染仍是导致发病的重要原因,并限制了充分透析。两种最常用的腹膜透析(PD)导管是盘绕型和直管型PD导管。现有研究结果相互矛盾。
本研究旨在观察两种导管类型的临床结局和死亡率。本研究设计为双向队列研究。共有126例接受PD治疗的患者参与研究,其中75例接受直管型PD导管,51例接受盘绕型PD导管。主要结局是导管存活情况,次要结局包括PD失败、导管相关感染和全因死亡率。
在盘绕型导管组中,30例(40%)患者出现导管故障,而直管型导管组有15例(29.4%)患者出现导管故障。然而,Kaplan-Meier生存曲线所代表的生存函数未显示出任何统计学意义(=0.659)。在盘绕型PD导管组中,13例(17.3%)出现PD失败,与直管型PD导管组的9例(17.6%)病例相当(=1.000)。两组的导管相关感染情况相似。两组之间的死亡率也相似(=0.777)。
盘绕型和直管型PD导管的结局没有差异。