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以深静脉血栓形成表现的直肠鳞状细胞癌意外复发。

An unexpected recurrence of rectal squamous cell cancer presenting as deep vein thrombosis.

作者信息

Kimyaghalam Ali, Singer Kiara, Kania Thomas, Malekpour Fatemeh

机构信息

Division of Vascular Surgery, Department of Surgery, Staten Island University Hospital, Staten Island, NY.

出版信息

J Vasc Surg Cases Innov Tech. 2023 Apr 19;9(2):101142. doi: 10.1016/j.jvscit.2023.101142. eCollection 2023 Jun.

DOI:10.1016/j.jvscit.2023.101142
PMID:37235170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10205761/
Abstract

Tumor thrombus is an uncommon oncologic complication and is exceedingly rare in the setting of colorectal cancer. We present the case of a 71-year-old woman with a significant oncologic history, including rectal squamous cell cancer, who presented with left lower extremity deep vein thrombosis. She underwent left lower extremity venography and thrombectomy of the left common iliac vein. Pathologic examination revealed fragments of squamous cell carcinoma embedded in an organizing thrombus. A covered stent was placed in the common iliac vein across the internal iliac vein origin. Positron emission tomography-computed tomography confirmed mediastinal and retroperitoneal lymphadenopathy, which was managed with adjuvant carboplatin and paclitaxel chemotherapy.

摘要

肿瘤血栓是一种罕见的肿瘤并发症,在结直肠癌患者中极为罕见。我们报告一例71岁女性患者,她有重要的肿瘤病史,包括直肠鳞状细胞癌,此次因左下肢深静脉血栓形成就诊。她接受了左下肢静脉造影和左髂总静脉血栓切除术。病理检查发现鳞状细胞癌碎片嵌入正在机化的血栓中。在髂总静脉横跨髂内静脉起始处放置了覆膜支架。正电子发射断层扫描-计算机断层扫描证实存在纵隔和腹膜后淋巴结病变,给予辅助卡铂和紫杉醇化疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/5796733ffa20/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/ffc571e50644/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/a9aa7dc0fd70/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/5796733ffa20/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/ffc571e50644/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/a9aa7dc0fd70/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9be9/10205761/5796733ffa20/gr3.jpg

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本文引用的文献

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Venous and Arterial Thromboembolism in Patients With Cancer: : State-of-the-Art Review.癌症患者的静脉和动脉血栓栓塞:最新综述
JACC CardioOncol. 2021 Apr 20;3(2):173-190. doi: 10.1016/j.jaccao.2021.03.001. eCollection 2021 Jun.
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Histopathologic analysis of extracted thrombi from deep venous thrombosis and pulmonary embolism: Mechanisms and timing.深静脉血栓和肺栓塞中提取血栓的组织病理学分析:机制和时间。
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Venous thromboembolism in cancer patients: report of baseline data from the multicentre, prospective Cancer-VTE Registry.
癌症患者静脉血栓栓塞症:多中心前瞻性癌症-静脉血栓栓塞症登记研究的基线数据报告。
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Lancet Oncol. 2019 Oct;20(10):e566-e581. doi: 10.1016/S1470-2045(19)30336-5. Epub 2019 Sep 3.
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Squamous cell carcinoma of the renal pelvis with inferior vena cava and iliac vein tumor thrombus.肾盂鳞状细胞癌伴下腔静脉及髂静脉肿瘤血栓形成。
Can J Urol. 2009 Dec;16(6):4958-61.
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Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients.住院癌症患者静脉血栓栓塞的发生率、危险因素及趋势
Cancer. 2007 Nov 15;110(10):2339-46. doi: 10.1002/cncr.23062.
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