尿细胞学检查的准确性如何？
How accurate is urine cytology?
作者信息
Curling M, Broome G, Hendry W F
出版信息
J R Soc Med. 1986 Jun;79(6):336-8. doi: 10.1177/014107688607900609.
Exfoliative urinary cytology was performed on 260 new cases of histologically proven urothelial cancer. The site, size, shape and histological grade of the tumours were documented, and they were classified by the TNM system. Overall, urine cytology was positive in 135 (52%), suspicious in 28 (11%) and negative in 97 (38%) cases. Malignant cells were found most often when the urothelial tumours were large, papillary and solid, moderately or poorly differentiated and invasive (T2-4). Most upper tract tumours and those situated in bladder diverticula had positive urinary cytology. This study confirms that exfoliative urinary cytology is useful in detecting the more malignant bladder tumours including in-situ carcinoma, and other tumours in less accessible parts of the urinary tract.
对260例经组织学证实的尿路上皮癌新病例进行了脱落尿细胞学检查。记录了肿瘤的部位、大小、形状和组织学分级，并根据TNM系统进行分类。总体而言，尿细胞学检查阳性135例（52%），可疑28例（11%），阴性97例（38%）。当尿路上皮肿瘤较大、呈乳头状和实性、中度或低分化且浸润性（T2-4）时，最常发现恶性细胞。大多数上尿路肿瘤和位于膀胱憩室内的肿瘤尿细胞学检查呈阳性。本研究证实，脱落尿细胞学检查有助于检测包括原位癌在内的恶性程度较高的膀胱肿瘤以及尿路较难触及部位的其他肿瘤。
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