通过平衡放射性核素心室造影评估特发性扩张型和缺血性心肌病患者的右心室功能。

Evaluation of right ventricular function in patients with idiopathic dilated and ischemic cardiomyopathy by equilibrium radionuclide ventriculography.

作者信息

Caglar N, Araki H, Nagata Y, Hisano R, Fukuyama T, Nakamura M

出版信息

Jpn Heart J. 1986 Jan;27(1):1-9. doi: 10.1536/ihj.27.1.

DOI:10.1536/ihj.27.1

Abstract

We performed equilibrium radionuclide ventriculography in 12 patients with idiopathic dilated cardiomyopathy, 11 patients with ischemic cardiomyopathy and 11 normal subjects to determine whether measurements of right ventricular function could be used to distinguish dilated cardiomyopathy from ischemic cardiomyopathy. The left ventricular ejection fraction in patients with dilated cardiomyopathy (26 +/- 8%, mean +/- SD) or ischemic cardiomyopathy (32 +/- 5%) was significantly lower than in normals (69 +/- 6%, p less than 0.001). The right ventricular ejection fraction (RVEF) in normals was 57 +/- 7%. RVEF was decreased in 11 of 12 patients with dilated cardiomyopathy and the mean value (32 +/- 10%) was significantly lower than that in patients with ischemic cardiomyopathy (56 +/- 7%, p less than 0.001), none of whom had decreased RVEF. Our data show that right ventricular dysfunction commonly exists in patients with dilated cardiomyopathy but not in patients with ischemic cardiomyopathy. This finding may be useful in the differentiation between dilated and ischemic cardiomyopathy.

摘要

我们对12例特发性扩张型心肌病患者、11例缺血性心肌病患者及11名正常受试者进行了平衡放射性核素心室造影，以确定右心室功能测量值是否可用于区分扩张型心肌病与缺血性心肌病。扩张型心肌病患者（26±8%，均值±标准差）或缺血性心肌病患者（32±5%）的左心室射血分数显著低于正常受试者（69±6%，p<0.001）。正常受试者的右心室射血分数（RVEF）为57±7%。12例扩张型心肌病患者中有11例RVEF降低，其平均值（32±10%）显著低于缺血性心肌病患者（56±7%，p<0.001），缺血性心肌病患者中无一例RVEF降低。我们的数据表明，右心室功能障碍常见于扩张型心肌病患者，而不见于缺血性心肌病患者。这一发现可能有助于区分扩张型心肌病和缺血性心肌病。