卵泡早期初级体感皮层兴奋与抑制功能的性别差异：一项初步研究。
Sex Differences in Excitatory and Inhibitory Function in the Primary Somatosensory Cortex during the Early Follicular Phase: A Preliminary Study.
作者信息
Anazawa Sayaka, Yamashiro Koya, Makibuchi Taiki, Ikarashi Koyuki, Fujimoto Tomomi, Ochi Genta, Sato Daisuke
机构信息
Field of Health and Sports, Graduate School of Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-Ku, Niigata 950-3198, Japan.
Department of Health and Sports, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-Ku, Niigata 950-3198, Japan.
出版信息
Brain Sci. 2023 May 5;13(5):761. doi: 10.3390/brainsci13050761.
BACKGROUND AND OBJECTIVES
We examined sex differences in the excitatory and inhibitory functions of the primary somatosensory cortex (S1) between males and females during the early follicular phase, when estradiol hormones are unaffected.
METHODS
Fifty participants (25 males and 25 females) underwent measurement of somatosensory evoked potentials (SEPs) and paired-pulse inhibition (PPI) in the S1; SEPs and PPI were elicited by constant current square-wave pulses (0.2 ms duration) delivered to the right median nerve by electrical stimulation. Paired-pulse stimulation occurred at 30- and 100-ms interstimulus intervals. Participants were randomly presented with 1500 (500 stimuli each) single- and paired-pulse stimuli at 2 Hz.
RESULTS
The N20 amplitude was significantly larger in female subjects than in male subjects, and the PPI-30 ms was significantly potentiated in female subjects compared to that in male subjects.
CONCLUSIONS
The excitatory and inhibitory functions in S1 differ between male and female subjects, at least during the early follicular phase.
背景与目的
我们研究了在卵泡早期（此时雌二醇激素未受影响），男性和女性初级体感皮层（S1）的兴奋性和抑制性功能的性别差异。
方法
50名参与者（25名男性和25名女性）接受了S1区体感诱发电位（SEP）和配对脉冲抑制（PPI）的测量；SEP和PPI由通过电刺激施加到右侧正中神经的恒流方波脉冲（持续时间0.2毫秒）诱发。配对脉冲刺激以30毫秒和100毫秒的刺激间隔进行。参与者以2赫兹的频率随机接受1500次（每次500次刺激）单脉冲和配对脉冲刺激。
结果
女性受试者的N20波幅显著大于男性受试者，与男性受试者相比，女性受试者的PPI-30毫秒显著增强。
结论
至少在卵泡早期，S1区的兴奋性和抑制性功能在男性和女性受试者之间存在差异。
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