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一名女性青少年的巨大盆腔肿物:骨外尤文肉瘤的非典型表现及成功治疗

Large Pelvic Mass in a Female Adolescent: Atypical Presentation and Successful Treatment of Extraskeletal Ewing Sarcoma.

作者信息

Perelli Federica, Vizzielli Giuseppe, Cavaliere Anna Franca, Restaino Stefano, Scambia Giovanni, Zannoni Gian Franco, Arciuolo Damiano, Gallotta Valerio

机构信息

Obstetrics and Gynecology Unit, Ospedale Santa Maria Annunziata, USL Toscana Centro, Bagno a Ripoli, 50012 Firenze, Italy.

Clinic of Obstetrics and Gynecology, S. Maria della Misericordia University Hospital, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), 33100 Udine, Italy.

出版信息

Healthcare (Basel). 2023 May 10;11(10):1373. doi: 10.3390/healthcare11101373.

DOI:10.3390/healthcare11101373
PMID:37239656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10218326/
Abstract

Extraskeletal Ewing sarcoma is a rare soft tissue tumor primarily affecting pediatric patients. The treatment is currently based on a multidisciplinary approach which allows, in cases of localized disease, good survival rates. We report the case of a 15-year-old female patient with a rapidly growing suspected pelvic mass misdiagnosed following the preliminary radiological exams, which assessed the findings as a mass of ovarian origin. The girl underwent surgery and, thanks to histopathological, immunohistochemical and real-time polymerase chain reaction (RT-PCR) examinations, it was possible to make the right diagnosis and to administer the best treatment in terms of surgery, chemotherapy and radiotherapy, obtaining a long disease-free interval and no recurrence to date.

摘要

骨外尤文肉瘤是一种罕见的软组织肿瘤,主要影响儿童患者。目前的治疗基于多学科方法,对于局限性疾病患者,该方法可带来较好的生存率。我们报告了一例15岁女性患者的病例,其盆腔有一个快速生长的可疑肿块,初步放射学检查误诊为卵巢来源的肿块。该女孩接受了手术,通过组织病理学、免疫组织化学和实时聚合酶链反应(RT-PCR)检查,得以做出正确诊断,并在手术、化疗和放疗方面给予最佳治疗,获得了较长的无病间期,且迄今为止未复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/d183c4c202d4/healthcare-11-01373-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/77ebbf130c4d/healthcare-11-01373-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/f70f51c85de2/healthcare-11-01373-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/3ebe682e23b5/healthcare-11-01373-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/5f4c29ac7647/healthcare-11-01373-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/d183c4c202d4/healthcare-11-01373-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/77ebbf130c4d/healthcare-11-01373-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/f70f51c85de2/healthcare-11-01373-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/3ebe682e23b5/healthcare-11-01373-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/5f4c29ac7647/healthcare-11-01373-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/10218326/d183c4c202d4/healthcare-11-01373-g005.jpg

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本文引用的文献

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Colorectal Dis. 2023 Jul;25(7):1336-1348. doi: 10.1111/codi.16571. Epub 2023 Apr 8.
2
Editorial: Methods in gynecological oncology.社论:妇科肿瘤学中的方法
Front Oncol. 2023 Mar 9;13:1167088. doi: 10.3389/fonc.2023.1167088. eCollection 2023.
3
Fertility-sparing options for cancer patients.癌症患者的保留生育力选择。
病例报告:伴有……种系致病变异的骨外尤因肉瘤
Front Oncol. 2024 Oct 8;14:1422605. doi: 10.3389/fonc.2024.1422605. eCollection 2024.
4
Editorial: Update in pediatric gynecology.社论:儿科妇科的进展
Front Surg. 2024 Mar 21;11:1391435. doi: 10.3389/fsurg.2024.1391435. eCollection 2024.
Abdom Radiol (NY). 2023 May;48(5):1618-1628. doi: 10.1007/s00261-023-03839-8. Epub 2023 Mar 8.
4
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.ETS 转录因子 ETV6 限制 EWS-FLI 的转录活性,从而促进尤因肉瘤的发生。
Nat Cell Biol. 2023 Feb;25(2):285-297. doi: 10.1038/s41556-022-01059-8. Epub 2023 Jan 19.
5
NCCN Guidelines® Insights: Ovarian Cancer, Version 3.2022.NCCN 指南®洞察:卵巢癌,第 3.2022 版。
J Natl Compr Canc Netw. 2022 Sep;20(9):972-980. doi: 10.6004/jnccn.2022.0047.
6
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Int J Mol Sci. 2021 Nov 12;22(22):12248. doi: 10.3390/ijms222212248.
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Int J Gynecol Cancer. 2021 Jul;31(7):961-982. doi: 10.1136/ijgc-2021-002565. Epub 2021 Jun 10.
8
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