Yagiela J A, Bilger P A
Lab Anim Sci. 1986 Jun;36(3):303-5.
A full-body restraining device was constructed that permits the short-term recording of physiologic data (respiration, electrocardiogram, arterial blood pressure, and electroencephalogram) in unanesthetized rats. A plaster cast of a freshly killed 160 g rat was made and cut to yield a base and two side pieces. Using the assembled cast as a custom tray, an alginate impression of the rat was taken. Replicas of the cast pieces were then made of plastic. Animals to be tested were anesthetized briefly, placed in the restraining device, and allowed to waken. Results with 400 animals demonstrate the feasibility of recording physiologic data during acute studies in conscious rats.
制作了一种全身约束装置，可在未麻醉的大鼠中短期记录生理数据（呼吸、心电图、动脉血压和脑电图）。制作了一只刚处死的160克大鼠的石膏模型，并将其切割成一个底座和两个侧片。以组装好的模型作为定制托盘，获取大鼠的藻酸盐印模。然后用塑料制作模型部件的复制品。待测试的动物先进行短暂麻醉，放入约束装置中，然后让其苏醒。对400只动物的测试结果证明了在清醒大鼠的急性研究中记录生理数据的可行性。
