Cárdenas-Rojas Martha I, Guzmán-Esquivel José, Murillo-Zamora Efrén
Unidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Villa de Álvarez 28984, Mexico.
J Clin Med. 2023 May 22;12(10):3593. doi: 10.3390/jcm12103593.
Children, although mostly affected mildly or asymptomatically, have also developed severe coronavirus disease 2019 (COVID-19). This study aims to assess potential predictors of intensive care unit (ICU) admission in a large population ( = 21,121) of children aged 0-9 years with laboratory-confirmed disease. We performed a cross-sectional analysis of a publicly available dataset derived from the normative epidemiological surveillance of COVID-19 in Mexico. The primary binary outcome of interest was admission to the ICU due to respiratory failure. Results showed that immunosuppressed children and those with a personal history of cardiovascular disease had a higher likelihood of being admitted to the ICU, while increasing age and the pandemic duration were associated with a lower likelihood of admission. The study's results have the potential to inform clinical decision-making and enhance management and outcomes for children affected by COVID-19 in Mexico.
儿童虽然大多症状轻微或无症状，但也出现了严重的2019冠状病毒病（COVID-19）。本研究旨在评估在一大群（n = 21121）0至9岁实验室确诊患病儿童中，入住重症监护病房（ICU）的潜在预测因素。我们对来自墨西哥COVID-19规范流行病学监测的公开可用数据集进行了横断面分析。感兴趣的主要二元结局是因呼吸衰竭入住ICU。结果显示，免疫抑制儿童和有心血管疾病个人史的儿童入住ICU的可能性更高，而年龄增长和疫情持续时间与入住可能性较低相关。该研究结果有可能为临床决策提供信息，并改善墨西哥受COVID-19影响儿童的管理和预后。
