Manno B R, Manno J E, Dempsey C A
J Anal Toxicol. 1986 May-Jun;10(3):116-9. doi: 10.1093/jat/10.3.116.
A thin layer chromatographic (TLC) method for the high volume screening of urine for methylphenidate (Ritalin) abuse is presented. The method utilizes charcoal extraction of ritalinic acid from urine and a simple test-tube methylation step for the conversion of the ritalinic acid to methylphenidate. The methylphenidate is then subjected to a routine TLC drug procedure for subsequent qualitative identification.
本文介绍了一种用于大量筛查尿液中哌醋甲酯（利他林）滥用情况的薄层色谱（TLC）方法。该方法利用从尿液中提取哌醋甲酯酸的活性炭萃取法以及一个简单的试管甲基化步骤，将哌醋甲酯酸转化为哌醋甲酯。然后，对哌醋甲酯进行常规的TLC药物检测程序，以进行后续的定性鉴定。
