Guizhou Medical University, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education & Guizhou Provincial Engineering Research Center of Ecological Food Innovation & School of Public Health, Guiyang, 550025, China.
The Affiliated Hospital of Guizhou Medical University, Department of Breast Surgery, Guiyang, 550004, China.
Sci Data. 2023 May 27;10(1):334. doi: 10.1038/s41597-023-02253-5.
Breast cancer (BC) is one of the major public health challenges worldwide. Studies that address the new evidence on trends of BC are of great importance for preventing and controlling the occurrence and development of diseases and improving health. The aim of this study was to analyze the outcomes for the global burden of disease (GBD), incidence, deaths, and risk factors for BC from 1990 to 2019, and predict the GBD of BC until 2050 to inform global BC control planning efforts. In this study, the results show that the regions with low levels of socio-demographic index (SDI) will have the largest disease burden of BC in the future. The leading global risk factor for death attributable to BC in 2019 was metabolic risks, followed by behavioral risks. This study supports the worldwide urgent need for comprehensive cancer prevention and control strategies to reduce exposure, early screening, and improve treatment to effectively reduce the GBD of BC.
乳腺癌（BC）是全球主要的公共卫生挑战之一。研究新出现的关于 BC 趋势的证据对于预防和控制疾病的发生和发展以及改善健康状况具有重要意义。本研究旨在分析 1990 年至 2019 年全球疾病负担（GBD）、发病率、死亡率以及乳腺癌的风险因素，并预测 2050 年之前 GBD 的情况，为全球乳腺癌控制规划工作提供信息。本研究结果表明，未来社会人口统计学指数（SDI）水平较低的地区将面临最大的乳腺癌疾病负担。2019 年导致乳腺癌死亡的全球主要风险因素是代谢风险，其次是行为风险。本研究支持全球紧急需要制定综合癌症防控策略，以减少暴露、早期筛查并改善治疗，从而有效降低乳腺癌的 GBD。
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