低密度脂蛋白内吞作用存在缺陷的体细胞突变体的分离 - Suppr

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Isolation of somatic cell mutants with defects in the endocytosis of low-density lipoprotein.

作者信息

Krieger M

出版信息

Methods Enzymol. 1986;129:227-37. doi: 10.1016/0076-6879(86)29072-2.

DOI:10.1016/0076-6879(86)29072-2

PMID:3724540

Abstract

摘要

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Isolation of somatic cell mutants with defects in the endocytosis of low-density lipoprotein.低密度脂蛋白内吞作用存在缺陷的体细胞突变体的分离

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Receptor-mediated endocytosis of low density lipoprotein: somatic cell mutants define multiple genes required for expression of surface-receptor activity.低密度脂蛋白的受体介导内吞作用：体细胞突变体定义了表面受体活性表达所需的多个基因。

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Use of radiation suicide to isolate constitutive and temperature-sensitive conditional Chinese hamster ovary cell mutants with defects in the endocytosis of low density lipoprotein.利用辐射自杀法分离低密度脂蛋白内吞缺陷的组成型和温度敏感型条件性中国仓鼠卵巢细胞突变体。

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Unusual forms of low density lipoprotein receptors in hamster cell mutants with defects in the receptor structural gene.仓鼠细胞突变体中低密度脂蛋白受体的异常形式，这些突变体的受体结构基因存在缺陷。

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Receptor-mediated delivery of photoprotective agents by low-density lipoprotein.

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Complementation of mutations in the LDL pathway of receptor-mediated endocytosis by cocultivation of LDL receptor-defective hamster cell mutants.通过低密度脂蛋白受体缺陷型仓鼠细胞突变体的共培养对受体介导的内吞作用的低密度脂蛋白途径中的突变进行互补。

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