Queensland Health, Sunshine Coast University Hospital, Queensland, Sunshine Coast, Australia.
Australas J Dermatol. 2023 Aug;64(3):400-403. doi: 10.1111/ajd.14086. Epub 2023 May 29.
Hypereosinophilic syndrome describes a process in which eosinophils in the peripheral blood are persistently increased, with variable clinical manifestations. Finding efficacious treatments for this disease can be challenging. This case describes a 72-year-old man with idiopathic hypereosinophilic syndrome with cutaneous manifestations who was successfully treated with dupilumab as a single agent therapy. There was complete clinical and biochemical resolution of disease (eosinophils levels decreased from 4.13 to 0.92) without complications.
高嗜酸性粒细胞综合征是一种外周血嗜酸性粒细胞持续增多的疾病，具有多种可变的临床表现。找到有效的治疗方法具有挑战性。本病例报告了一名 72 岁的特发性高嗜酸性粒细胞综合征伴皮肤表现的患者，他接受了度普利尤单抗单药治疗，获得了成功。疾病完全得到临床和生化缓解（嗜酸性粒细胞水平从 4.13 降至 0.92），无并发症。
