Department of Internal Medicine, Christian Medical College and Hospital, Ludhiana, Punjab, India.
Department of Haematology, Christian Medical College and Hospital, Ludhiana, Punjab, India.
Trop Doct. 2023 Oct;53(4):512-516. doi: 10.1177/00494755231177487. Epub 2023 May 29.
Kimura's disease is a chronic, benign inflammatory condition of the subcutaneous tissue. It presents as painless, subcutaneous nodules of the head and neck, which are firm, painless, and may be single or multiple. It is most commonly seen in young adult Asian men. The nodes remain stable or may slowly enlarge over time. Elevated serum immunoglobulin E (IgE) levels, peripheral blood eosinophilia and lymphoid proliferation with eosinophilic infiltration on histopathological examination are the characteristic features. Spontaneous regression is usually seen. The diagnosis of Kimura's disease can be difficult and misleading, and it is important not to ignore histopathological features.
木村病是一种慢性、良性的皮下组织炎症性疾病。它表现为头颈部无痛性、皮下结节,质地坚硬,无触痛,可单发或多发。它最常见于年轻的成年亚裔男性。结节保持稳定或可能随时间缓慢增大。特征性表现为血清免疫球蛋白 E(IgE)水平升高、外周血嗜酸性粒细胞增多和淋巴细胞增生伴嗜酸性粒细胞浸润。通常会自发消退。木村病的诊断可能具有挑战性和误导性,重要的是不要忽视组织病理学特征。