Heinämäki A A, Muhonen A S, Piha R S
Neurochem Res. 1986 Apr;11(4):535-42. doi: 10.1007/BF00965323.
Levels of free amino acids were determined quantitatively in whole ocular tissues of the rat eye with aid of a sensitive amino acid analyzer. The tissues studied were the retina, vitreous, lens, iris-ciliary body, and cornea. The retina and lens contained a more concentrated free amino acid pool than other tissues. The neuroactive amino acids taurine. GABA, glutamic acid, aspartic acid, and glycine were clearly enriched in the retina. Taurine was the most abundant amino acid in all five tissues studied, and its high concentration in non-neural tissues, especially the lens, suggests that it must have other functions as well as neurotransmitter ones in the rat eye.
借助灵敏的氨基酸分析仪对大鼠眼球的全眼组织中的游离氨基酸水平进行了定量测定。所研究的组织包括视网膜、玻璃体、晶状体、虹膜睫状体和角膜。视网膜和晶状体中的游离氨基酸池比其他组织更为浓缩。神经活性氨基酸牛磺酸、γ-氨基丁酸、谷氨酸、天冬氨酸和甘氨酸在视网膜中明显富集。牛磺酸是所研究的所有五种组织中含量最丰富的氨基酸，其在非神经组织尤其是晶状体中的高浓度表明，它在大鼠眼中除了具有神经递质功能外，肯定还具有其他功能。
